Gene description for LSM14B
Gene name LSM14B, SCD6 homolog B (S. cerevisiae)
Gene symbol LSM14B
Other names/aliases C20orf40
FAM61B
FT005
LSM13
RAP55B
bA11M20.3
Species Homo sapiens
 Database cross references - LSM14B
ExoCarta ExoCarta_149986
Vesiclepedia VP_149986
Entrez Gene 149986
HGNC 15887
UniProt Q9BX40  
 LSM14B identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for LSM14B
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA binding GO:0003729 IBA
    protein binding GO:0005515 IPI
Biological Process
    ovarian follicle development GO:0001541 ISS
    regulation of translation GO:0006417 IEA
    oogenesis GO:0048477 ISS
    membraneless organelle assembly GO:0140694 ISS
    maternal mRNA clearance GO:0141065 ISS
    meiotic cell cycle process involved in oocyte maturation GO:1903537 ISS
Subcellular Localization
    cytoplasmic ribonucleoprotein granule GO:0036464 ISS
    ribonucleoprotein complex GO:1990904 IEA
 Experiment description of studies that identified LSM14B in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for LSM14B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 DDX6 1656
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 FBL 2091
Proximity Label-MS Homo sapiens
4 LBR 3930
Affinity Capture-MS Homo sapiens
5 YBX1 4904
Affinity Capture-MS Homo sapiens
6 PRM2  
Affinity Capture-MS Homo sapiens
7 NTRK1 4914
Affinity Capture-MS Homo sapiens
8 MYCN  
Affinity Capture-MS Homo sapiens
9 ICK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 TCEANC  
Two-hybrid Homo sapiens
11 CLPX 10845
Affinity Capture-MS Homo sapiens
12 LGR4 55366
Affinity Capture-MS Homo sapiens
13 CLEC3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 CSDE1 7812
Affinity Capture-MS Homo sapiens
15 FBXL6  
Affinity Capture-MS Homo sapiens
16 Iffo1  
Affinity Capture-MS Mus musculus
17 CPEB1  
Proximity Label-MS Homo sapiens
18 XPO1 7514
Affinity Capture-MS Homo sapiens
19 AURKA 6790
Affinity Capture-MS Homo sapiens
20 LSM14A 26065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 RPL37 6167
Affinity Capture-MS Homo sapiens
22 LGALS1 3956
Affinity Capture-MS Homo sapiens
23 PDHB 5162
Co-fractionation Homo sapiens
24 EIF4ENIF1 56478
Affinity Capture-MS Homo sapiens
25 SEMG2 6407
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 IPO5 3843
Co-fractionation Homo sapiens
27 C17orf85  
Affinity Capture-MS Homo sapiens
28 SOX2  
Affinity Capture-MS Homo sapiens
29 SEPT9 10801
Affinity Capture-MS Homo sapiens
30 SEMG1 6406
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 CAPZB 832
Co-fractionation Homo sapiens
32 RPS20 6224
Proximity Label-MS Homo sapiens
33 C1QBP 708
Affinity Capture-MS Homo sapiens
34 MYC  
Affinity Capture-MS Homo sapiens
35 HECW2  
Affinity Capture-MS Homo sapiens
36 WDYHV1  
Two-hybrid Homo sapiens
37 OGT 8473
Reconstituted Complex Homo sapiens
38 CASP3 836
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 PSMD9 5715
Affinity Capture-MS Homo sapiens
40 CHCHD2  
Affinity Capture-MS Homo sapiens
41 GTF3C2  
Affinity Capture-MS Homo sapiens
42 POLDIP2 26073
Affinity Capture-MS Homo sapiens
43 FBXW7  
Affinity Capture-MS Homo sapiens
44 DDX54 79039
Affinity Capture-MS Homo sapiens
45 BHLHA15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 SMC1A 8243
Affinity Capture-MS Homo sapiens
47 POU5F1  
Affinity Capture-MS Homo sapiens
48 CHCHD10  
Affinity Capture-MS Homo sapiens
49 CTNNA1 1495
Co-fractionation Homo sapiens
50 PPP2R1A 5518
Co-fractionation Homo sapiens
51 C1qbp 12261
Affinity Capture-MS Mus musculus
52 PTCH1  
Affinity Capture-MS Homo sapiens
53 PHF8  
Affinity Capture-MS Homo sapiens
54 PRMT1 3276
Affinity Capture-MS Homo sapiens
55 LUC7L 55692
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 CEBPA  
Protein-peptide Homo sapiens
57 SIRT3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 HUWE1 10075
Affinity Capture-MS Homo sapiens
59 ZMYND11 10771
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which LSM14B is involved
No pathways found





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