Gene description for ZNF114
Gene name zinc finger protein 114
Gene symbol ZNF114
Other names/aliases -
Species Homo sapiens
 Database cross references - ZNF114
ExoCarta ExoCarta_163071
Vesiclepedia VP_163071
Entrez Gene 163071
HGNC 12894
MIM 603996
UniProt Q8NC26  
 ZNF114 identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for ZNF114
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of DNA-templated transcription GO:0006355 IBA
    regulation of transcription by RNA polymerase II GO:0006357 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified ZNF114 in sEVs
1
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for ZNF114
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZNF114 163071
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 PPP2CA 5515
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 MYO15B 80022
Two-hybrid Homo sapiens
4 KRTAP10-6  
Two-hybrid Homo sapiens
5 SUFU 51684
Two-hybrid Homo sapiens
6 CUEDC1 404093
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 TPPP 11076
Two-hybrid Homo sapiens
8 CLIP4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
9 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 PPP2R1B 5519
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 TRIM28 10155
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 CCDC84 338657
Two-hybrid Homo sapiens
13 MAP7 9053
Two-hybrid Homo sapiens
14 KIAA0753  
Two-hybrid Homo sapiens
15 PPP2R2C 5522
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 EGFR 1956
Affinity Capture-MS Homo sapiens
17 CBX5 23468
Affinity Capture-MS Homo sapiens
18 KLHL2 11275
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
19 ZNF8  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ZNF114 is involved
PathwayEvidenceSource
Gene expression (Transcription) TAS Reactome
Generic Transcription Pathway TAS Reactome
RNA Polymerase II Transcription TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here