Gene description for Ngfr
Gene name	nerve growth factor receptor (TNFR superfamily, member 16)
Gene symbol	Ngfr
Other names/aliases	LNGFR Tnfrsf16 p75 p75NGFR p75NTR
Species	Mus musculus
Database cross references - Ngfr
ExoCarta	ExoCarta_18053
Vesiclepedia	VP_18053
Entrez Gene	18053
Ngfr identified in sEVs derived from the following tissue/cell type
Melanoma cells	34957415
Melanoma cells	34957415
Melanoma cells	34957415
Melanoma cells	34957415

Gene ontology annotations for Ngfr

Molecular Function     amyloid-beta binding GO:0001540 ISO     death receptor activity GO:0005035 IBA     death receptor activity GO:0005035 IDA     death receptor activity GO:0005035 ISO     neurotrophin TRKA receptor binding GO:0005168 ISO     protein binding GO:0005515 IPI     calmodulin binding GO:0005516 ISO     calmodulin binding GO:0005516 ISS     coreceptor activity GO:0015026 IBA     coreceptor activity GO:0015026 IEA     coreceptor activity GO:0015026 ISO     small GTPase binding GO:0031267 IDA     ubiquitin protein ligase binding GO:0031625 IEA     ubiquitin protein ligase binding GO:0031625 ISO     identical protein binding GO:0042802 ISO     neurotrophin binding GO:0043121 ISO     protein-containing complex binding GO:0044877 ISO     nerve growth factor binding GO:0048406 IBA     nerve growth factor binding GO:0048406 IDA     nerve growth factor binding GO:0048406 ISO     preprotein binding GO:0070678 ISO Biological Process     intracellular glucose homeostasis GO:0001678 IMP     hair follicle development GO:0001942 IMP     intracellular protein transport GO:0006886 IMP     Rho protein signal transduction GO:0007266 IBA     Rho protein signal transduction GO:0007266 IEA     Rho protein signal transduction GO:0007266 ISO     axon guidance GO:0007411 IMP     central nervous system development GO:0007417 IMP     circadian rhythm GO:0007623 IEP     fibroblast growth factor receptor signaling pathway GO:0008543 IMP     regulation of gene expression GO:0010468 IMP     positive regulation of neuron projection development GO:0010976 ISO     negative regulation of neuron projection development GO:0010977 ISO     detection of temperature stimulus GO:0016048 IMP     negative regulation of angiogenesis GO:0016525 ISO     nerve development GO:0021675 IMP     negative regulation of cell migration GO:0030336 IEA     negative regulation of cell migration GO:0030336 ISO     hair follicle morphogenesis GO:0031069 IMP     positive regulation of myelination GO:0031643 ISO     positive regulation of synaptic transmission, cholinergic GO:0032224 ISO     circadian regulation of gene expression GO:0032922 IMP     cellular response to oxidative stress GO:0034599 ISO     positive regulation of Rho protein signal transduction GO:0035025 ISO     dorsal aorta development GO:0035907 IMP     negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 IMP     odontogenesis of dentin-containing tooth GO:0042475 IMP     positive regulation of odontogenesis of dentin-containing tooth GO:0042488 IMP     glucose homeostasis GO:0042593 IMP     positive regulation of apoptotic process GO:0043065 ISO     negative regulation of apoptotic process GO:0043066 ISO     positive regulation of MAPK cascade GO:0043410 ISO     negative regulation of neuron apoptotic process GO:0043524 ISO     skin development GO:0043588 IMP     positive regulation of neuron differentiation GO:0045666 ISO     fibroblast proliferation GO:0048144 IMP     positive regulation of fibroblast proliferation GO:0048146 IMP     neuron apoptotic process GO:0051402 IEA     neuron apoptotic process GO:0051402 ISO     negative regulation of hair follicle development GO:0051799 IMP     positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 ISO     negative regulation of mitochondrial depolarization GO:0051902 ISO     positive regulation of synaptic transmission, glutamatergic GO:0051968 ISO     negative regulation of dendritic spine development GO:0061000 ISO     presynaptic modulation of chemical synaptic transmission GO:0099171 IDA     presynaptic modulation of chemical synaptic transmission GO:0099171 IMP     positive regulation of protein localization to nucleus GO:1900182 IEA     positive regulation of protein localization to nucleus GO:1900182 ISO     positive regulation of miRNA transcription GO:1902895 IEA     positive regulation of miRNA transcription GO:1902895 ISO     negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:1903588 IEA     negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:1903588 ISO     cellular response to amyloid-beta GO:1904646 IEA     cellular response to amyloid-beta GO:1904646 ISO     positive regulation of neural precursor cell proliferation GO:2000179 ISO     regulation of reactive oxygen species metabolic process GO:2000377 ISO     positive regulation of excitatory postsynaptic potential GO:2000463 ISO     positive regulation of cysteine-type endopeptidase activity GO:2001056 ISO     positive regulation of apoptotic signaling pathway GO:2001235 IDA Subcellular Localization     nuclear envelope GO:0005635 ISO     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 IDA     mitochondrion GO:0005739 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 ISS     plasma membrane GO:0005886 TAS     cell-cell junction GO:0005911 IDA     external side of plasma membrane GO:0009897 ISO     cell surface GO:0009986 IBA     cell surface GO:0009986 IDA     postsynaptic density GO:0014069 IDA     growth cone GO:0030426 IEA     neuromuscular junction GO:0031594 IDA     neuromuscular junction GO:0031594 IMP     neuromuscular junction GO:0031594 ISO     dendrite membrane GO:0032590 ISO     neuronal cell body membrane GO:0032809 ISO     presynaptic membrane GO:0042734 ISO     dendritic spine GO:0043197 IEA     perikaryon GO:0043204 IEA     perikaryon GO:0043204 ISO     clathrin-coated endocytic vesicle GO:0045334 ISO     presynapse GO:0098793 IEA