Gene description for Wnt11
Gene name	wingless-type MMTV integration site family, member 11
Gene symbol	Wnt11
Other names/aliases	-
Species	Mus musculus
Database cross references - Wnt11
ExoCarta	ExoCarta_22411
Vesiclepedia	VP_22411
Entrez Gene	22411
UniProt	P48615
Wnt11 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Wnt11

Molecular Function     GTPase activator activity GO:0005096 ISO     signaling receptor binding GO:0005102 TAS     frizzled binding GO:0005109 IBA     cytokine activity GO:0005125 IBA     protein binding GO:0005515 IPI     protein kinase activator activity GO:0030295 IEA     protein kinase activator activity GO:0030295 ISO Biological Process     osteoblast differentiation GO:0001649 IGI     kidney development GO:0001822 IDA     epithelial to mesenchymal transition GO:0001837 IGI     primary heart field specification GO:0003138 IGI     secondary heart field specification GO:0003139 IGI     outflow tract morphogenesis GO:0003151 IMP     ventricular septum development GO:0003281 IGI     atrial septum development GO:0003283 IGI     protein phosphorylation GO:0006468 ISO     apoptotic process GO:0006915 IMP     signal transduction GO:0007165 ISO     signal transduction GO:0007165 ISS     signal transduction GO:0007165 TAS     cell-cell signaling GO:0007267 TAS     animal organ morphogenesis GO:0009887 TAS     mesenchymal cell proliferation GO:0010463 IMP     neuron differentiation GO:0030182 IBA     bone mineralization GO:0030282 IGI     negative regulation of cell growth GO:0030308 ISO     adrenal gland development GO:0030325 IEA     negative regulation of cell migration GO:0030336 ISO     response to nutrient levels GO:0031667 IEA     positive regulation of transforming growth factor beta2 production GO:0032915 IMP     protein localization to cell surface GO:0034394 ISO     intracellular signal transduction GO:0035556 ISS     non-canonical Wnt signaling pathway GO:0035567 IMP     positive regulation of apoptotic process GO:0043065 IMP     positive regulation of GTPase activity GO:0043547 ISO     cell fate commitment GO:0045165 IBA     maintenance of epithelial cell apical/basal polarity GO:0045199 IGI     negative regulation of DNA-templated transcription GO:0045892 ISO     positive regulation of DNA-templated transcription GO:0045893 ISO     positive regulation of DNA-templated transcription GO:0045893 ISS     paraxial mesoderm formation GO:0048341 IGI     notochord morphogenesis GO:0048570 IGI     embryonic skeletal system development GO:0048706 IEA     artery morphogenesis GO:0048844 IMP     positive regulation of stress fiber assembly GO:0051496 ISO     roof of mouth development GO:0060021 IMP     convergent extension involved in axis elongation GO:0060028 IGI     canonical Wnt signaling pathway GO:0060070 IBA     canonical Wnt signaling pathway GO:0060070 IDA     cloacal septation GO:0060197 IEA     ventricular septum morphogenesis GO:0060412 IMP     lung-associated mesenchyme development GO:0060484 IEA     ureteric bud morphogenesis GO:0060675 IEA     somite development GO:0061053 IGI     neuroendocrine cell differentiation GO:0061101 ISO     neuroendocrine cell differentiation GO:0061101 ISS     secondary palate development GO:0062009 ISO     secondary palate development GO:0062009 ISS     bicellular tight junction assembly GO:0070830 IMP     cellular response to mechanical stimulus GO:0071260 IDA     stem cell proliferation GO:0072089 IMP     mesonephric duct development GO:0072177 IEA     negative regulation of mesenchymal cell proliferation GO:0072201 IMP     positive regulation of protein kinase C signaling GO:0090037 ISO     negative regulation of canonical Wnt signaling pathway GO:0090090 IDA     negative regulation of canonical Wnt signaling pathway GO:0090090 ISO     negative regulation of canonical Wnt signaling pathway GO:0090090 ISS     negative regulation of fibroblast growth factor production GO:0090272 IMP     epithelial cell apoptotic process GO:1904019 IMP     positive regulation of epithelial cell apoptotic process GO:1904037 IMP     negative regulation of stem cell proliferation GO:2000647 IMP Subcellular Localization     extracellular region GO:0005576 IDA     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IBA     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISS     extracellular matrix GO:0031012 IDA