Gene description for Tcf4
Gene name	transcription factor 4
Gene symbol	Tcf4
Other names/aliases	5730422P05Rik ASP-I2 E2-2 E2.2 ITF-2 ITF-2b ITF2 ME2 MITF-2A MITF-2B SEF-2 SEF2 SEF2-1 TFE Tcf-4 bHLHb19
Species	Mus musculus
Database cross references - Tcf4
ExoCarta	ExoCarta_21413
Vesiclepedia	VP_21413
Entrez Gene	21413
UniProt	Q60722
Tcf4 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Tcf4

Molecular Function     RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000977 IMP     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 ISO     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IDA     TFIIB-class transcription factor binding GO:0001093 IDA     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IDA     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IMP     DNA binding GO:0003677 IDA     DNA binding GO:0003677 ISO     chromatin binding GO:0003682 IDA     double-stranded DNA binding GO:0003690 ISO     DNA-binding transcription factor activity GO:0003700 ISO     transcription corepressor activity GO:0003714 IDA     protein binding GO:0005515 IPI     beta-catenin binding GO:0008013 ISO     identical protein binding GO:0042802 IMP     identical protein binding GO:0042802 ISO     bHLH transcription factor binding GO:0043425 ISO     protein heterodimerization activity GO:0046982 IDA     E-box binding GO:0070888 IDA     sequence-specific double-stranded DNA binding GO:1990837 ISO Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IDA     regulation of DNA-templated transcription GO:0006355 IDA     regulation of transcription by RNA polymerase II GO:0006357 IBA     nervous system development GO:0007399 IEA     negative regulation of gene expression GO:0010629 IDA     negative regulation of angiogenesis GO:0016525 IDA     cell differentiation GO:0030154 IEA     endothelial cell activation GO:0042118 IDA     positive regulation of neuron differentiation GO:0045666 IDA     positive regulation of DNA-templated transcription GO:0045893 ISO     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IMP     positive regulation of transcription by RNA polymerase II GO:0045944 ISO     protein-DNA complex assembly GO:0065004 IDA     regulation of vascular endothelial growth factor signaling pathway GO:1900746 IDA Subcellular Localization     chromatin GO:0000785 IBA     chromatin GO:0000785 ISO     nucleus GO:0005634 IDA     nucleus GO:0005634 ISO     transcription regulator complex GO:0005667 IBA     transcription regulator complex GO:0005667 IDA     beta-catenin-TCF7L2 complex GO:0070369 ISO     beta-catenin-TCF complex GO:1990907 ISO