Gene description for Nars2
Gene name asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)
Gene symbol Nars2
Other names/aliases AI875199
Species Mus musculus
 Database cross references - Nars2
ExoCarta ExoCarta_244141
Vesiclepedia VP_244141
Entrez Gene 244141
UniProt Q8BGV0  
 Nars2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nars2
Molecular Function
    nucleic acid binding GO:0003676 IEA
    asparagine-tRNA ligase activity GO:0004816 IBA
    asparagine-tRNA ligase activity GO:0004816 ISS
    ATP binding GO:0005524 IEA
Biological Process
    asparaginyl-tRNA aminoacylation GO:0006421 IBA
    asparaginyl-tRNA aminoacylation GO:0006421 ISS
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 ISO
    mitochondrion GO:0005739 ISS
    mitochondrial matrix GO:0005759 IEA
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Nars2 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nars2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Tars 110960
Co-fractionation Mus musculus
2 Rars 104458
Co-fractionation Mus musculus
3 Sdcbp 53378
Co-fractionation Mus musculus
4 Mars 216443
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Nars2 is involved
No pathways found





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