Gene description for Rtcb
Gene name
RNA 2',3'-cyclic phosphate and 5'-OH ligase
Gene symbol
Rtcb
Other names/aliases
AI255213 AI463255 D10Wsu52e FAAP HSPC117
Species
Mus musculus
Database cross references - Rtcb
ExoCarta
ExoCarta_28088
Vesiclepedia
VP_28088
Entrez Gene
28088
UniProt
Q99LF4
Rtcb identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Rtcb
Experiment description of studies that identified Rtcb in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Rtcb
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Ddx1
104721
Co-fractionation
Mus musculus
2
U2af2
22185
Two-hybrid
Mus musculus
3
Kctd13
Affinity Capture-MS
Mus musculus
4
Mettl21e
Affinity Capture-MS
Mus musculus
5
2700060E02Rik
68045
Co-fractionation
Mus musculus
6
Atxn1
Proximity Label-MS
Mus musculus
7
Fam98b
68215
Co-fractionation
Mus musculus
8
Eed
Affinity Capture-MS
Mus musculus
9
Nmt1
Co-fractionation
Mus musculus
10
Polr1c
Co-fractionation
Mus musculus
11
Krt18
16668
Co-fractionation
Mus musculus
12
Trmt10c
Co-fractionation
Mus musculus
13
Nanog
Affinity Capture-MS
Mus musculus
14
Fancd2
Affinity Capture-MS
Mus musculus
15
Rars2
Co-fractionation
Mus musculus
16
Pef1
Two-hybrid
Mus musculus
View the network
image/svg+xml
Pathways in which Rtcb is involved
No pathways found