Gene description for RCOR2
Gene name REST corepressor 2
Gene symbol RCOR2
Other names/aliases -
Species Homo sapiens
 Database cross references - RCOR2
ExoCarta ExoCarta_283248
Vesiclepedia VP_283248
Entrez Gene 283248
HGNC 27455
MIM 616019
UniProt Q8IZ40  
 RCOR2 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for RCOR2
Molecular Function
    transcription corepressor activity GO:0003714 IBA
    protein binding GO:0005515 IPI
    enzyme binding GO:0019899 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    negative regulation of DNA-templated transcription GO:0045892 IBA
Subcellular Localization
    histone deacetylase complex GO:0000118 IBA
    transcription regulator complex GO:0005667 IBA
 Experiment description of studies that identified RCOR2 in sEVs
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for RCOR2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HMG20B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 MECP2 4204
Affinity Capture-MS Homo sapiens
3 ZNF174  
Affinity Capture-MS Homo sapiens
4 HDAC2 3066
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 GFI1B  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
6 CRYAA 1409
Affinity Capture-MS Homo sapiens
7 HDAC1 3065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 CTBP1 1487
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 TAF1  
Affinity Capture-MS Homo sapiens
10 TRIM24  
Affinity Capture-MS Homo sapiens
11 ZSCAN5A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 KDM1A 23028
Proximity Label-MS Homo sapiens
13 PRDM16 63976
Affinity Capture-MS Homo sapiens
14 PDGFRL 5157
Affinity Capture-MS Homo sapiens
15 SP110  
Affinity Capture-MS Homo sapiens
16 ZMYND8 23613
Affinity Capture-MS Homo sapiens
17 DCAF12L2  
Affinity Capture-MS Homo sapiens
18 SUMO2 6613
Reconstituted Complex Homo sapiens
19 S100B 6285
Affinity Capture-MS Homo sapiens
20 NOL4  
Affinity Capture-MS Homo sapiens
21 DYNLL2 140735
Affinity Capture-MS Homo sapiens
22 HMG20A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 ZMYM2  
Affinity Capture-MS Homo sapiens
24 DYNLL1 8655
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 ECE2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RCOR2 is involved
No pathways found





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