Gene description for MMP7
Gene name	matrix metallopeptidase 7
Gene symbol	MMP7
Other names/aliases	MMP-7 MPSL1 PUMP-1
Species	Homo sapiens
Database cross references - MMP7
ExoCarta	ExoCarta_4316
Vesiclepedia	VP_4316
Entrez Gene	4316
HGNC	7174
MIM	178990
UniProt	P09237
MMP7 identified in sEVs derived from the following tissue/cell type
Colorectal cancer cells	17956143
Pancreatic duct fluid	29339034

Gene ontology annotations for MMP7

Molecular Function     endopeptidase activity GO:0004175 IDA     metalloendopeptidase activity GO:0004222 IBA     metalloendopeptidase activity GO:0004222 TAS     serine-type endopeptidase activity GO:0004252 TAS     protein binding GO:0005515 IPI     metallopeptidase activity GO:0008237 IDA     zinc ion binding GO:0008270 IEA Biological Process     antibacterial peptide secretion GO:0002779 IEA     antibacterial peptide biosynthetic process GO:0002780 IEA     proteolysis GO:0006508 IDA     membrane protein ectodomain proteolysis GO:0006509 IMP     response to xenobiotic stimulus GO:0009410 IEA     extracellular matrix disassembly GO:0022617 TAS     extracellular matrix organization GO:0030198 IBA     positive regulation of cell migration GO:0030335 IDA     collagen catabolic process GO:0030574 IBA     collagen catabolic process GO:0030574 TAS     membrane protein intracellular domain proteolysis GO:0031293 IMP     regulation of cell population proliferation GO:0042127 IEA     defense response to Gram-negative bacterium GO:0050829 IEA     defense response to Gram-positive bacterium GO:0050830 IEA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IBA     extracellular matrix GO:0031012 IEA     extracellular exosome GO:0070062 HDA