|
Gene description for Lrrc8b |
| Gene name |
leucine rich repeat containing 8 family, member B |
| Gene symbol |
Lrrc8b |
| Other names/aliases |
R75581 Ta-lrrp mKIAA0231 |
| Species |
Mus musculus |
Database cross references - Lrrc8b |
| ExoCarta |
ExoCarta_433926 |
| Vesiclepedia |
VP_433926 |
| Entrez Gene |
433926 |
| UniProt |
Q5DU41
|
Lrrc8b identified in sEVs derived from the following tissue/cell type |
|
Melanoma cells
|
34957415
|
|
Melanoma cells
|
34957415
|
Gene ontology annotations for Lrrc8b |
|
|
Experiment description of studies that identified Lrrc8b in sEVs |
| 1 |
| Experiment ID |
1117 |
| MISEV standards |
|
✘
|
Biophysical techniques |
|
✔
Cd81|Icam1
|
Enriched markers |
|
✘
|
Negative markers |
|
✔
NTA
|
Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
34957415
|
| Organism |
Mus musculus |
| Experiment description |
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism |
| Authors |
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H." |
| Journal name |
Nat Cancer
|
| Publication year |
2021 |
| Sample |
Melanoma cells |
| Sample name |
B16-F1R2 |
| Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Western blotting Mass spectrometry |
|
|
| 2 |
| Experiment ID |
1118 |
| MISEV standards |
|
✘
|
Biophysical techniques |
|
✔
Cd81|Icam1
|
Enriched markers |
|
✘
|
Negative markers |
|
✔
NTA
|
Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
34957415
|
| Organism |
Mus musculus |
| Experiment description |
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism |
| Authors |
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H." |
| Journal name |
Nat Cancer
|
| Publication year |
2021 |
| Sample |
Melanoma cells |
| Sample name |
B16-F1R2 |
| Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Western blotting Mass spectrometry |
|
|
Protein-protein interactions for Lrrc8b |
|
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Pathways in which Lrrc8b is involved |
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