Gene description for UBE2Q1
Gene name ubiquitin-conjugating enzyme E2Q family member 1
Gene symbol UBE2Q1
Other names/aliases GTAP
NICE-5
PRO3094
UBE2Q
Species Homo sapiens
 Database cross references - UBE2Q1
ExoCarta ExoCarta_55585
Vesiclepedia VP_55585
Entrez Gene 55585
HGNC 15698
UniProt Q7Z7E8  
 UBE2Q1 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for UBE2Q1
Molecular Function
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    ubiquitin conjugating enzyme activity GO:0061631 IBA
Biological Process
    protein polyubiquitination GO:0000209 IBA
    suckling behavior GO:0001967 IEA
    embryo implantation GO:0007566 IEA
    mating behavior GO:0007617 IEA
    fertilization GO:0009566 IEA
    reproductive system development GO:0061458 IEA
    prolactin secretion GO:0070459 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
    cytosol GO:0005829 IEA
    filopodium GO:0030175 IEA
 Experiment description of studies that identified UBE2Q1 in sEVs
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for UBE2Q1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 STUB1 10273
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 CSTL1  
Affinity Capture-MS Homo sapiens
4 C1QTNF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 LYPD3 27076
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 PSMC3 5702
Co-fractionation Homo sapiens
7 GPR17 2840
Affinity Capture-MS Homo sapiens
8 IFT20 90410
Affinity Capture-MS Homo sapiens
9 LARP4B 23185
Affinity Capture-MS Homo sapiens
10 MAGEA9  
Affinity Capture-MS Homo sapiens
11 C3AR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 SRPRB 58477
Affinity Capture-MS Homo sapiens
13 GPR161  
Affinity Capture-MS Homo sapiens
14 PSMD11 5717
Co-fractionation Homo sapiens
15 RNF31 55072
Reconstituted Complex Homo sapiens
16 PSMC2 5701
Co-fractionation Homo sapiens
17 S100A2 6273
Affinity Capture-MS Homo sapiens
18 HSP90AB1 3326
Co-fractionation Homo sapiens
19 FHL3 2275
Two-hybrid Homo sapiens
20 UBC 7316
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
21 USP11 8237
Affinity Capture-MS Homo sapiens
22 HCST  
Affinity Capture-MS Homo sapiens
23 HTR2C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 TCEAL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 RNF7  
Two-hybrid Homo sapiens
26 PSMD14 10213
Co-fractionation Homo sapiens
27 ERP44 23071
Affinity Capture-MS Homo sapiens
28 TACR3  
Affinity Capture-MS Homo sapiens
29 MFSD11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 OGT 8473
Reconstituted Complex Homo sapiens
31 IRF2BPL 64207
Two-hybrid Homo sapiens
32 SNW1 22938
Affinity Capture-MS Homo sapiens
33 UBE2Q2 92912
Affinity Capture-MS Homo sapiens
34 KIAA0368 23392
Two-hybrid Homo sapiens
35 RNF26  
Two-hybrid Homo sapiens
36 PRSS21  
Affinity Capture-MS Homo sapiens
37 PSMC4 5704
Co-fractionation Homo sapiens
38 SYT2  
Affinity Capture-MS Homo sapiens
39 ITCH 83737
Reconstituted Complex Homo sapiens
40 MDM2  
Reconstituted Complex Homo sapiens
41 COX4I1 1327
Affinity Capture-MS Homo sapiens
42 HYPM  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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