Gene description for UBFD1
Gene name ubiquitin family domain containing 1
Gene symbol UBFD1
Other names/aliases UBPH
Species Homo sapiens
 Database cross references - UBFD1
ExoCarta ExoCarta_56061
Vesiclepedia VP_56061
Entrez Gene 56061
HGNC 30565
UniProt O14562  
 UBFD1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for UBFD1
Molecular Function
    RNA binding GO:0003723 HDA
    cadherin binding GO:0045296 HDA
 Experiment description of studies that identified UBFD1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for UBFD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 YWHAH 7533
Co-fractionation Homo sapiens
2 Dctn5  
Affinity Capture-MS Mus musculus
3 NPEPPS 9520
Co-fractionation Homo sapiens
4 UBE2S  
Co-fractionation Homo sapiens
5 PSMC3 5702
Co-fractionation Homo sapiens
6 Psmb5 19173
Affinity Capture-MS Mus musculus
7 G6PD 2539
Co-fractionation Homo sapiens
8 LDHB 3945
Co-fractionation Homo sapiens
9 FSD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 PSMC4 5704
Affinity Capture-MS Homo sapiens
11 ZNF622 90441
Co-fractionation Homo sapiens
12 TMEM248 55069
Affinity Capture-MS Homo sapiens
13 FERMT2 10979
Co-fractionation Homo sapiens
14 NFKBIA  
Affinity Capture-MS Homo sapiens
15 PAK2 5062
Co-fractionation Homo sapiens
16 PBDC1 51260
Co-fractionation Homo sapiens
17 SHFM1 7979
Affinity Capture-MS Homo sapiens
18 Klc4  
Affinity Capture-MS Mus musculus
19 APEX1 328
Affinity Capture-RNA Homo sapiens
20 UBC 7316
Reconstituted Complex Homo sapiens
21 CSE1L 1434
Co-fractionation Homo sapiens
22 TGM2 7052
Co-fractionation Homo sapiens
23 EIF4E 1977
Co-fractionation Homo sapiens
24 MVK 4598
Co-fractionation Homo sapiens
25 HSPA1A 3303
Cross-Linking-MS (XL-MS) Homo sapiens
26 PDPK1 5170
Co-fractionation Homo sapiens
27 SNRPF 6636
Co-fractionation Homo sapiens
28 HNRNPK 3190
Co-fractionation Homo sapiens
29 ERP44 23071
Co-fractionation Homo sapiens
30 CKB 1152
Co-fractionation Homo sapiens
31 MAP2K3 5606
Cross-Linking-MS (XL-MS) Homo sapiens
32 GNS 2799
Co-fractionation Homo sapiens
33 TBCB 1155
Co-fractionation Homo sapiens
34 VCL 7414
Co-fractionation Homo sapiens
35 RPA3 6119
Proximity Label-MS Homo sapiens
36 PMVK 10654
Co-fractionation Homo sapiens
37 KRIT1 889
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 SLC9A3R1 9368
Co-fractionation Homo sapiens
39 GNAI3 2773
Co-fractionation Homo sapiens
40 RPA4  
Proximity Label-MS Homo sapiens
41 CDH1 999
Proximity Label-MS Homo sapiens
42 YWHAQ 10971
Co-fractionation Homo sapiens
43 Calml3  
Affinity Capture-MS Mus musculus
44 Pcna 18538
Affinity Capture-MS Mus musculus
45 ISOC1 51015
Co-fractionation Homo sapiens
46 YWHAG 7532
Co-fractionation Homo sapiens
47 SCLY  
Co-fractionation Homo sapiens
48 Ufl1  
Affinity Capture-MS Mus musculus
49 SH2D4A 63898
Co-fractionation Homo sapiens
50 EIF5 1983
Co-fractionation Homo sapiens
51 CNDP2 55748
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which UBFD1 is involved
No pathways found





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