Gene description for RAB3IL1
Gene name RAB3A interacting protein (rabin3)-like 1
Gene symbol RAB3IL1
Other names/aliases GRAB
Species Homo sapiens
 Database cross references - RAB3IL1
ExoCarta ExoCarta_5866
Vesiclepedia VP_5866
Entrez Gene 5866
HGNC 9780
UniProt Q8TBN0  
 RAB3IL1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for RAB3IL1
Molecular Function
    guanyl-nucleotide exchange factor activity GO:0005085 IBA
    guanyl-nucleotide exchange factor activity GO:0005085 IDA
    guanyl-nucleotide exchange factor activity GO:0005085 TAS
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
Biological Process
    protein transport GO:0015031 IEA
Subcellular Localization
    cytosol GO:0005829 TAS
 Experiment description of studies that identified RAB3IL1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for RAB3IL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 OPTN 10133
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 GNB2 2783
Affinity Capture-MS Homo sapiens
3 NOTCH2NL 388677
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
4 PDLIM7 9260
Affinity Capture-MS Homo sapiens
5 TRAPPC9 83696
Affinity Capture-MS Homo sapiens
6 PSMA3 5684
Two-hybrid Homo sapiens
7 CTDSP1 58190
Two-hybrid Homo sapiens
8 TRAPPC10 7109
Affinity Capture-MS Homo sapiens
9 C2orf68  
Two-hybrid Homo sapiens
10 CCDC102A 92922
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 SYCE1  
Affinity Capture-MS Homo sapiens
12 PPFIA3 8541
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 EIF1AX 1964
Affinity Capture-MS Homo sapiens
14 C14orf119  
Two-hybrid Homo sapiens
15 CCDC57 284001
Two-hybrid Homo sapiens
16 FAM49B 51571
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 KRT34  
Two-hybrid Homo sapiens
18 NBPF19  
Two-hybrid Homo sapiens
19 RAB3IL1 5866
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
20 TRAPPC2L 51693
Affinity Capture-MS Homo sapiens
21 ODF2 4957
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 FHL5 9457
Two-hybrid Homo sapiens
23 KLHDC10 23008
Affinity Capture-MS Homo sapiens
24 MAP3K1 4214
Biochemical Activity Homo sapiens
25 NUDT18  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
26 ATG4C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 SUGP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 TRAPPC1 58485
Affinity Capture-MS Homo sapiens
29 SATB2  
Two-hybrid Homo sapiens
30 GPX1 2876
Affinity Capture-MS Homo sapiens
31 RAB8A 4218
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 COG6 57511
Two-hybrid Homo sapiens
33 MB21D2  
Affinity Capture-MS Homo sapiens
34 PPIL4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 STX1A 6804
Two-hybrid Homo sapiens
36 MLLT1 4298
Affinity Capture-MS Homo sapiens
37 CYSRT1 375791
Two-hybrid Homo sapiens
38 TRAPPC4 51399
Affinity Capture-MS Homo sapiens
39 TRAPPC3 27095
Affinity Capture-MS Homo sapiens
40 RAB11A 8766
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
41 TIGD7  
Two-hybrid Homo sapiens
42 RAB3IP  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 AMOT 154796
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 AMOTL1 154810
Affinity Capture-MS Homo sapiens
45 KRT40  
Two-hybrid Homo sapiens
46 TMEM102  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 IP6K1 9807
Reconstituted Complex Homo sapiens
48 AMPD2 271
Affinity Capture-MS Homo sapiens
49 RAB3A 5864
Two-hybrid Homo sapiens
50 HSF2BP  
Two-hybrid Homo sapiens
51 MTUS2 23281
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
52 GDF5 8200
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 KRTAP6-3  
Two-hybrid Homo sapiens
54 TTC7B 145567
Two-hybrid Homo sapiens
View the network image/svg+xml



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