Gene description for RYR3
Gene name	ryanodine receptor 3
Gene symbol	RYR3
Other names/aliases	RYR-3
Species	Homo sapiens
Database cross references - RYR3
ExoCarta	ExoCarta_6263
Vesiclepedia	VP_6263
Entrez Gene	6263
HGNC	10485
MIM	180903
UniProt	Q15413
RYR3 identified in sEVs derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for RYR3

Molecular Function     ryanodine-sensitive calcium-release channel activity GO:0005219 IBA     ryanodine-sensitive calcium-release channel activity GO:0005219 ISS     ryanodine-sensitive calcium-release channel activity GO:0005219 TAS     calcium ion binding GO:0005509 IEA     calmodulin binding GO:0005516 IEA     intracellularly gated calcium channel activity GO:0015278 IMP     calcium-induced calcium release activity GO:0048763 ISS Biological Process     calcium ion transport GO:0006816 IMP     intracellular calcium ion homeostasis GO:0006874 IEA     striated muscle contraction GO:0006941 IBA     release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 IBA     calcium-mediated signaling GO:0019722 IEA     release of sequestered calcium ion into cytosol GO:0051209 ISS     protein homotetramerization GO:0051289 ISS     calcium ion transmembrane transport GO:0070588 ISS     cellular response to calcium ion GO:0071277 ISS     cellular response to magnesium ion GO:0071286 ISS     cellular response to caffeine GO:0071313 ISS     cellular response to ATP GO:0071318 ISS Subcellular Localization     smooth endoplasmic reticulum GO:0005790 IBA     membrane GO:0016020 ISS     Z disc GO:0030018 IBA     sarcoplasmic reticulum membrane GO:0033017 IBA     sarcoplasmic reticulum membrane GO:0033017 ISS     sarcoplasmic reticulum membrane GO:0033017 ISS     sarcoplasmic reticulum membrane GO:0033017 TAS     calcium channel complex GO:0034704 IBA     sarcolemma GO:0042383 IBA