Gene description for ARHGAP9
Gene name Rho GTPase activating protein 9
Gene symbol ARHGAP9
Other names/aliases 10C
RGL1
Species Homo sapiens
 Database cross references - ARHGAP9
ExoCarta ExoCarta_64333
Vesiclepedia VP_64333
Entrez Gene 64333
HGNC 14130
MIM 610576
UniProt Q9BRR9  
 ARHGAP9 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ARHGAP9
Molecular Function
    GTPase activator activity GO:0005096 IBA
    GTPase activator activity GO:0005096 IDA
    GTPase activator activity GO:0005096 TAS
    protein binding GO:0005515 IPI
    phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 IDA
Biological Process
    small GTPase-mediated signal transduction GO:0007264 IBA
    regulation of small GTPase mediated signal transduction GO:0051056 TAS
Subcellular Localization
    extracellular region GO:0005576 TAS
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IBA
    secretory granule lumen GO:0034774 TAS
 Experiment description of studies that identified ARHGAP9 in sEVs
1
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ARHGAP9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TOMM40 10452
Affinity Capture-MS Homo sapiens
2 SUFU 51684
Affinity Capture-MS Homo sapiens
3 SLIRP 81892
Affinity Capture-MS Homo sapiens
4 MAPK14 1432
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
5 ABI3 51225
Two-hybrid Homo sapiens
6 SMN1 6606
Affinity Capture-MS Homo sapiens
7 HADHB 3032
Affinity Capture-MS Homo sapiens
8 RBPMS 11030
Two-hybrid Homo sapiens
9 GRB2 2885
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
10 HOMEZ  
Two-hybrid Homo sapiens
11 MAPK1 5594
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
12 ASAP1 50807
Affinity Capture-MS Homo sapiens
13 ZYX 7791
Affinity Capture-MS Homo sapiens
14 FASLG 356
Protein-peptide Homo sapiens
15 GOLGA6A  
Two-hybrid Homo sapiens
16 TAB1 10454
Affinity Capture-MS Homo sapiens
17 PPP1R9B 84687
Affinity Capture-MS Homo sapiens
18 HSD17B10 3028
Affinity Capture-MS Homo sapiens
19 STOML2 30968
Affinity Capture-MS Homo sapiens
20 SNRPF 6636
Affinity Capture-MS Homo sapiens
21 BOLA2 552900
Affinity Capture-MS Homo sapiens
22 KPNA2 3838
Affinity Capture-MS Homo sapiens
23 APP 351
Reconstituted Complex Homo sapiens
24 GOLGA6L9  
Two-hybrid Homo sapiens
25 TOMM22 56993
Affinity Capture-MS Homo sapiens
26 SNRNP70 6625
Affinity Capture-MS Homo sapiens
27 TSC22D4 81628
Two-hybrid Homo sapiens
28 PRDX3 10935
Affinity Capture-MS Homo sapiens
29 SMAD9  
Two-hybrid Homo sapiens
30 CYSRT1 375791
Two-hybrid Homo sapiens
31 CRKL 1399
Affinity Capture-MS Homo sapiens
32 NME7 29922
Two-hybrid Homo sapiens
33 RPN1 6184
Affinity Capture-MS Homo sapiens
34 SNRPC 6631
Two-hybrid Homo sapiens
35 RAC1 5879
FRET Homo sapiens
36 AKT1 207
Biochemical Activity Homo sapiens
37 MRPL38  
Two-hybrid Homo sapiens
38 Mapk1 116590
Affinity Capture-MS Rattus norvegicus
39 FHL2 2274
Two-hybrid Homo sapiens
40 SMARCC2 6601
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here