Gene description for Cndp2
Gene name CNDP dipeptidase 2 (metallopeptidase M20 family)
Gene symbol Cndp2
Other names/aliases 0610010E05Rik
C76600
Cn2
Dip-2
Pep-1
Pep1
Species Mus musculus
 Database cross references - Cndp2
ExoCarta ExoCarta_66054
Vesiclepedia VP_66054
Entrez Gene 66054
UniProt Q9D1A2  
 Cndp2 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Cndp2
Molecular Function
    carboxypeptidase activity GO:0004180 IEA
    peptidase activity GO:0008233 IDA
    dipeptidase activity GO:0016805 IBA
    dipeptidase activity GO:0016805 IDA
    dipeptidase activity GO:0016805 ISO
    metal ion binding GO:0046872 IEA
    metallodipeptidase activity GO:0070573 IEA
Biological Process
    proteolysis GO:0006508 IBA
    proteolysis GO:0006508 IDA
    proteolysis GO:0006508 ISO
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytosol GO:0005829 IBA
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Cndp2 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Cndp2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Scly  
Co-fractionation Mus musculus
2 Usp14 59025
Co-fractionation Mus musculus
3 Eed  
Affinity Capture-MS Mus musculus
4 Rps6ka1 20111
Co-fractionation Mus musculus
5 Mvd  
Co-fractionation Mus musculus
6 Fancd2  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



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