Gene description for EPM2AIP1
Gene name EPM2A (laforin) interacting protein 1
Gene symbol EPM2AIP1
Other names/aliases -
Species Homo sapiens
 Database cross references - EPM2AIP1
ExoCarta ExoCarta_9852
Vesiclepedia VP_9852
Entrez Gene 9852
HGNC 19735
MIM 607911
UniProt Q7L775  
 EPM2AIP1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for EPM2AIP1
Molecular Function
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
Biological Process
    glycogen biosynthetic process GO:0005978 IEA
    response to insulin GO:0032868 IEA
    positive regulation of glycogen biosynthetic process GO:0045725 IBA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasmic side of endoplasmic reticulum membrane GO:0098554 IEA
 Experiment description of studies that identified EPM2AIP1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for EPM2AIP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZBTB14  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 CITED1 4435
Affinity Capture-MS Homo sapiens
3 ZSCAN18  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 ACTN1 87
Two-hybrid Homo sapiens
5 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
6 EPM2AIP1 9852
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
7 RBMY1F  
Two-hybrid Homo sapiens
8 MAD2L1 4085
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
9 CBFA2T3  
Two-hybrid Homo sapiens
10 APPL2 55198
Two-hybrid Homo sapiens
11 HSF2BP  
Two-hybrid Homo sapiens
12 KCTD9  
Two-hybrid Homo sapiens
13 VPS52 6293
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
14 TNFAIP1 7126
Two-hybrid Homo sapiens
15 CSNK1A1 1452
Affinity Capture-MS Homo sapiens
16 REL 5966
Two-hybrid Homo sapiens
17 MAD2L1BP  
Affinity Capture-MS Homo sapiens
18 GFAP 2670
Two-hybrid Homo sapiens
19 PRTFDC1 56952
Two-hybrid Homo sapiens
20 MX1 4599
Two-hybrid Homo sapiens
21 TNKS 8658
Two-hybrid Homo sapiens
22 FHL3 2275
Two-hybrid Homo sapiens
23 USP54 159195
Two-hybrid Homo sapiens
24 CCNB1IP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
25 C1orf50  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
26 TRA2B 6434
Two-hybrid Homo sapiens
27 SOX2  
Affinity Capture-MS Homo sapiens
28 TRIM54  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
29 DHX40  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 ZIM2  
Two-hybrid Homo sapiens
31 LIN52  
Two-hybrid Homo sapiens
32 TRIM50  
Two-hybrid Homo sapiens
33 ZNF620  
Two-hybrid Homo sapiens
34 SERPINF1 5176
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
35 FAM20C 56975
Affinity Capture-MS Homo sapiens
36 CNTROB  
Two-hybrid Homo sapiens
37 PSMA7 5688
Two-hybrid Homo sapiens
38 NTRK1 4914
Affinity Capture-MS Homo sapiens
39 RAB24 53917
Affinity Capture-MS Homo sapiens
40 LDB2  
Two-hybrid Homo sapiens
41 NOC4L 79050
Two-hybrid Homo sapiens
42 KRT75 9119
Two-hybrid Homo sapiens
43 MEOX2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
44 CPSF7 79869
Two-hybrid Homo sapiens
45 DTX3  
Two-hybrid Homo sapiens
46 KCTD1 284252
Two-hybrid Homo sapiens
47 SWSAP1  
Two-hybrid Homo sapiens
48 Mad2l1 56150
Affinity Capture-MS Mus musculus
49 EMP2  
Two-hybrid Homo sapiens
50 OTUD7B 56957
Two-hybrid Homo sapiens
51 KRT16 3868
Two-hybrid Homo sapiens
52 MAGEA3  
Affinity Capture-MS Homo sapiens
53 RBMY1J  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which EPM2AIP1 is involved
No pathways found





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