Gene description for PLD3
Gene name phospholipase D family, member 3
Gene symbol PLD3
Other names/aliases AD19
HU-K4
HUK4
Species Homo sapiens
 Database cross references - PLD3
ExoCarta ExoCarta_23646
Vesiclepedia VP_23646
Entrez Gene 23646
HGNC 17158
MIM 615698
UniProt Q8IV08  
 PLD3 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Keratinocytes 19530224    
Keratinocytes 19530224    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Prostate cancer cells 25844599    
Saliva 19199708    
Urine 19056867    
 Gene ontology annotations for PLD3
Molecular Function
    phospholipase D activity GO:0004630 TAS
    protein binding GO:0005515 IPI
    single-stranded DNA 5'-3' DNA exonuclease activity GO:0045145 IDA
Biological Process
    immune system process GO:0002376 IEA
    DNA metabolic process GO:0006259 IEA
    inflammatory response GO:0006954 IEA
    myotube differentiation GO:0014902 IDA
    regulation of cytokine production involved in inflammatory response GO:1900015 ISS
Subcellular Localization
    Golgi membrane GO:0000139 IDA
    lysosomal membrane GO:0005765 IEA
    endoplasmic reticulum membrane GO:0005789 IDA
    early endosome membrane GO:0031901 IDA
    late endosome membrane GO:0031902 IDA
    lysosomal lumen GO:0043202 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified PLD3 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
15
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
16
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for PLD3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 SLFN11 91607
Affinity Capture-MS Homo sapiens
3 HACD3 51495
Affinity Capture-MS Homo sapiens
4 PPT1 5538
Affinity Capture-MS Homo sapiens
5 ITGB1 3688
Affinity Capture-MS Homo sapiens
6 HSD17B11 51170
Proximity Label-MS Homo sapiens
7 TK1 7083
Two-hybrid Homo sapiens
8 METTL7A 25840
Proximity Label-MS Homo sapiens
9 EIF2S3 1968
Co-fractionation Homo sapiens
10 OS9 10956
Affinity Capture-MS Homo sapiens
11 GJA1 2697
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 C3orf58 205428
Affinity Capture-MS Homo sapiens
13 PSME2 5721
Affinity Capture-MS Homo sapiens
14 RPA2 6118
Proximity Label-MS Homo sapiens
15 MAN1B1 11253
Affinity Capture-MS Homo sapiens
16 ATP12A 479
Affinity Capture-MS Homo sapiens
17 SRPR 6734
Affinity Capture-MS Homo sapiens
18 SURF4 6836
Affinity Capture-MS Homo sapiens
19 PLD4  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
20 SPNS1 83985
Affinity Capture-MS Homo sapiens
21 GJD3  
Proximity Label-MS Homo sapiens
22 DNAJC25 548645
Proximity Label-MS Homo sapiens
23 LTN1 26046
Affinity Capture-MS Homo sapiens
24 GCN1L1 10985
Affinity Capture-MS Homo sapiens
25 CPT1A 1374
Affinity Capture-MS Homo sapiens
26 TGFBR1 7046
Affinity Capture-MS Homo sapiens
27 TELO2 9894
Affinity Capture-MS Homo sapiens
28 QSOX2 169714
Affinity Capture-MS Homo sapiens
29 DNAJC10 54431
Proximity Label-MS Homo sapiens
30 B3GAT1  
Proximity Label-MS Homo sapiens
31 GP1BB 2812
Affinity Capture-MS Homo sapiens
32 LPGAT1 9926
Affinity Capture-MS Homo sapiens
33 MON2 23041
Affinity Capture-MS Homo sapiens
34 HGS 9146
Reconstituted Complex Homo sapiens
35 PGS1 9489
Affinity Capture-MS Homo sapiens
36 OPRM1 4988
Two-hybrid Homo sapiens
37 NPM1 4869
Proximity Label-MS Homo sapiens
38 TM9SF1 10548
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
39 PNPLA6 10908
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
40 PLD2 5338
Affinity Capture-Western Homo sapiens
41 SUN2 25777
Affinity Capture-MS Homo sapiens
42 FADS1 3992
Affinity Capture-MS Homo sapiens
43 TMEM192 201931
Affinity Capture-MS Homo sapiens
44 PDIA6 10130
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
45 NUDCD1 84955
Co-fractionation Homo sapiens
46 KIAA0368 23392
Affinity Capture-MS Homo sapiens
47 ACSL1 2180
Affinity Capture-MS Homo sapiens
48 MECP2 4204
Affinity Capture-MS Homo sapiens
49 MYCN  
Affinity Capture-MS Homo sapiens
50 MFSD10 10227
Affinity Capture-MS Homo sapiens
51 DNAAF5 54919
Affinity Capture-MS Homo sapiens
52 EBAG9 9166
Proximity Label-MS Homo sapiens
53 CLGN 1047
Affinity Capture-MS Homo sapiens
54 NCSTN 23385
Affinity Capture-MS Homo sapiens
55 FAM20C 56975
Affinity Capture-MS Homo sapiens
56 EMC1 23065
Affinity Capture-MS Homo sapiens
57 LMAN1 3998
Affinity Capture-MS Homo sapiens
58 UGGT1 56886
Affinity Capture-MS Homo sapiens
59 EXTL3 2137
Affinity Capture-MS Homo sapiens
60 ANXA7 310
Two-hybrid Homo sapiens
61 PPP5C 5536
Co-fractionation Homo sapiens
62 COX15 1355
Affinity Capture-MS Homo sapiens
63 FZD8 8325
Affinity Capture-MS Homo sapiens
64 CYB5D2  
Affinity Capture-MS Homo sapiens
65 HSP90B1 7184
Affinity Capture-MS Homo sapiens
66 PLD1 5337
Affinity Capture-Western Homo sapiens
67 TM9SF2 9375
Affinity Capture-MS Homo sapiens
68 TMTC3 160418
Affinity Capture-MS Homo sapiens
69 GPR35  
Two-hybrid Homo sapiens
70 CHPF2 54480
Affinity Capture-MS Homo sapiens
71 DNAJC5 80331
Proximity Label-MS Homo sapiens
72 TUBB2B 347733
Affinity Capture-MS Homo sapiens
73 UBXN8  
Affinity Capture-MS Homo sapiens
74 CLCC1 23155
Affinity Capture-MS Homo sapiens
75 FUBP1 8880
Co-fractionation Homo sapiens
76 PDS5A 23244
Affinity Capture-MS Homo sapiens
77 VCP 7415
Affinity Capture-MS Homo sapiens
78 TRIM21 6737
Affinity Capture-MS Homo sapiens
79 OGT 8473
Reconstituted Complex Homo sapiens
80 SCAMP2 10066
Affinity Capture-MS Homo sapiens
81 LEMD2 221496
Affinity Capture-MS Homo sapiens
82 HIST1H1E 3008
Cross-Linking-MS (XL-MS) Homo sapiens
83 ITM2C 81618
Affinity Capture-MS Homo sapiens
84 B3GALNT2 148789
Affinity Capture-MS Homo sapiens
85 SLC1A3 6507
Affinity Capture-MS Homo sapiens
86 NOMO3 408050
Affinity Capture-MS Homo sapiens
87 P4HB 5034
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
88 RPN1 6184
Proximity Label-MS Homo sapiens
89 EXT2 2132
Affinity Capture-MS Homo sapiens
90 ATP2B4 493
Affinity Capture-MS Homo sapiens
91 PTK7 5754
Affinity Capture-MS Homo sapiens
92 DNAJB5  
Proximity Label-MS Homo sapiens
93 SEC61B 10952
Proximity Label-MS Homo sapiens
94 SLC33A1 9197
Affinity Capture-MS Homo sapiens
95 DNAJB11 51726
Proximity Label-MS Homo sapiens
96 ZDHHC13 54503
Affinity Capture-MS Homo sapiens
97 EIF4A2 1974
Affinity Capture-MS Homo sapiens
98 PHB 5245
Affinity Capture-MS Homo sapiens
99 SEC63 11231
Proximity Label-MS Homo sapiens
100 NTRK1 4914
Affinity Capture-MS Homo sapiens
101 HSP90B2P  
Affinity Capture-MS Homo sapiens
102 TMEM30A 55754
Affinity Capture-MS Homo sapiens
103 LMBRD2 92255
Affinity Capture-MS Homo sapiens
104 RPN2 6185
Proximity Label-MS Homo sapiens
105 ERLEC1 27248
Affinity Capture-MS Homo sapiens
106 AGPAT1 10554
Affinity Capture-MS Homo sapiens
107 RAB5A 5868
Proximity Label-MS Homo sapiens
108 RAB34 83871
Affinity Capture-MS Homo sapiens
109 GPR89B 51463
Affinity Capture-MS Homo sapiens
110 LAMP1 3916
Proximity Label-MS Homo sapiens
111 MLYCD 23417
Co-fractionation Homo sapiens
112 BCAP31 10134
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 HSD3B7 80270
Proximity Label-MS Homo sapiens
114 CUL3 8452
Affinity Capture-MS Homo sapiens
115 GPD2 2820
Affinity Capture-MS Homo sapiens
116 STIM1 6786
Affinity Capture-MS Homo sapiens
117 TUBB4B 10383
Affinity Capture-MS Homo sapiens
118 PDIA3 2923
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
119 EGFR 1956
Affinity Capture-MS Homo sapiens
120 CNPY3 10695
Affinity Capture-MS Homo sapiens
121 SLC7A5 8140
Affinity Capture-MS Homo sapiens
122 FBXO6 26270
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 GLB1L2  
Affinity Capture-MS Homo sapiens
124 TMEM194A  
Affinity Capture-MS Homo sapiens
125 ABHD12 26090
Affinity Capture-MS Homo sapiens
126 ERP44 23071
Co-fractionation Homo sapiens
127 TM9SF3 56889
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
128 SLITRK5  
Affinity Capture-MS Homo sapiens
129 LSMEM2  
Affinity Capture-MS Homo sapiens
130 MYC  
Affinity Capture-MS Homo sapiens
131 RPA3 6119
Proximity Label-MS Homo sapiens
132 ATP2A1 487
Proximity Label-MS Homo sapiens
133 MPDU1 9526
Affinity Capture-MS Homo sapiens
134 NFKB1 4790
Reconstituted Complex Homo sapiens
135 HNRNPAB 3182
Cross-Linking-MS (XL-MS) Homo sapiens
136 DNAJC3 5611
Proximity Label-MS Homo sapiens
137 DNAJC1 64215
Proximity Label-MS Homo sapiens
138 B3GAT3 26229
Affinity Capture-MS Homo sapiens
139 STX4 6810
Proximity Label-MS Homo sapiens
140 GANAB 23193
Affinity Capture-MS Homo sapiens
141 LEMD3  
Affinity Capture-MS Homo sapiens
142 LMNA 4000
Proximity Label-MS Homo sapiens
143 ALG5 29880
Affinity Capture-MS Homo sapiens
144 RTN4 57142
Affinity Capture-MS Homo sapiens
145 MAGT1 84061
Affinity Capture-MS Homo sapiens
146 TTC13  
Affinity Capture-MS Homo sapiens
147 LBR 3930
Affinity Capture-MS Homo sapiens
148 APOA1BP 128240
Affinity Capture-MS Homo sapiens
149 MANEA 79694
Affinity Capture-MS Homo sapiens
150 NPTX1  
Affinity Capture-MS Homo sapiens
151 PRKCSH 5589
Affinity Capture-MS Homo sapiens
152 Tyw3  
Affinity Capture-MS Mus musculus
153 HNRNPH2 3188
Affinity Capture-MS Homo sapiens
154 FDFT1 2222
Affinity Capture-MS Homo sapiens
155 CERS1 10715
Affinity Capture-MS Homo sapiens
156 PDIA4 9601
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
157 SPP1 6696
Two-hybrid Homo sapiens
158 RSPRY1 89970
Affinity Capture-MS Homo sapiens
159 SEPN1 57190
Affinity Capture-MS Homo sapiens
160 SCAMP3 10067
Affinity Capture-MS Homo sapiens
161 DNAJA3 9093
Proximity Label-MS Homo sapiens
162 SOX4  
Two-hybrid Homo sapiens
163 PIGK 10026
Affinity Capture-MS Homo sapiens
164 CAV1 857
Proximity Label-MS Homo sapiens
165 PNPLA7  
Affinity Capture-MS Homo sapiens
166 ADAM15 8751
Affinity Capture-MS Homo sapiens
167 DOLPP1  
Affinity Capture-MS Homo sapiens
168 SLC38A7 55238
Affinity Capture-MS Homo sapiens
169 EDEM3 80267
Affinity Capture-MS Homo sapiens
170 ITGAV 3685
Affinity Capture-MS Homo sapiens
171 PLD3 23646
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
172 BCL2L1 598
Two-hybrid Homo sapiens
173 SEC62 7095
Proximity Label-MS Homo sapiens
174 HNRNPH3 3189
Co-fractionation Homo sapiens
175 SMCO4  
Two-hybrid Homo sapiens
176 TM7SF2  
Affinity Capture-MS Homo sapiens
177 EGFL7 51162
Affinity Capture-MS Homo sapiens
178 NME3 4832
Affinity Capture-MS Homo sapiens
179 CUL7 9820
Affinity Capture-MS Homo sapiens
180 HSP90AB4P 664618
Affinity Capture-MS Homo sapiens
181 PLD6  
Affinity Capture-Western Homo sapiens
182 CNIH3  
Two-hybrid Homo sapiens
183 ESYT1 23344
Affinity Capture-MS Homo sapiens
184 HSPA1B 3304
Affinity Capture-MS Homo sapiens
185 ARMC6 93436
Affinity Capture-MS Homo sapiens
186 SLC3A2 6520
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here