Gene ontology annotations for TK1
Experiment description of studies that identified TK1 in sEVs
1
Experiment ID
489
MISEV standards
✔
Biophysical techniques
✔
Enriched markers
✔
Negative markers
✔
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
490
MISEV standards
✔
Biophysical techniques
✔
Enriched markers
✔
Negative markers
✔
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
491
MISEV standards
✔
Biophysical techniques
✔
Enriched markers
✔
Negative markers
✔
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
492
MISEV standards
✔
Biophysical techniques
✔
Enriched markers
✔
Negative markers
✔
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
5
Experiment ID
1203
MISEV standards
✔
Biophysical techniques
✔
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34887515
Organism
Homo sapiens
Experiment description
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors
"Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Colorectal cancer cells
Sample name
DiFi
Isolation/purification methods
Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein miRNA
Methods used in the study
Western blotting Mass spectrometry RNA sequencing
6
Experiment ID
235
MISEV standards
✔
Biophysical techniques
✔
Enriched markers
✔
Negative markers
✔
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
7
Experiment ID
488
MISEV standards
✔
Biophysical techniques
✔
Enriched markers
✔
Negative markers
✔
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
Protein-protein interactions for TK1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
UBE2H
7328
Affinity Capture-MS
Homo sapiens
2
CENPB
1059
Two-hybrid
Homo sapiens
3
A1BG
1
Two-hybrid
Homo sapiens
4
APLP1
333
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
5
CLEC3B
7123
Two-hybrid
Homo sapiens
6
BOLA2
552900
Two-hybrid
Homo sapiens
7
JADE1
Two-hybrid
Homo sapiens
8
FBN3
84467
Two-hybrid
Homo sapiens
9
QARS
5859
Two-hybrid
Homo sapiens
10
JMJD1C
221037
Two-hybrid
Homo sapiens
11
TK1
7083
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
12
ATP6V1A
523
Two-hybrid
Homo sapiens
13
TSC2
7249
Two-hybrid
Homo sapiens
14
ZXDC
Two-hybrid
Homo sapiens
15
PKM
5315
Two-hybrid
Homo sapiens
16
COL11A2
1302
Two-hybrid
Homo sapiens
17
RPA2
6118
Proximity Label-MS
Homo sapiens
18
GLB1
2720
Two-hybrid
Homo sapiens
19
ALB
213
Two-hybrid
Homo sapiens
20
BOLA2B
654483
Two-hybrid
Homo sapiens
21
GDF9
2661
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
22
IGHM
3507
Two-hybrid
Homo sapiens
23
DACT1
51339
Two-hybrid
Homo sapiens
24
DYNC1I1
Two-hybrid
Homo sapiens
25
MRPL37
51253
Two-hybrid
Homo sapiens
26
KLHL23
Two-hybrid
Homo sapiens
27
NCF1
Affinity Capture-MS
Homo sapiens
28
SETDB1
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
29
APP
351
Reconstituted Complex
Homo sapiens
30
CCDC90B
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
31
CCDC43
124808
Affinity Capture-MS
Homo sapiens
32
CPNE6
9362
Two-hybrid
Homo sapiens
33
RBM48
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
34
RPS2
6187
Two-hybrid
Homo sapiens
35
RUVBL1
8607
Two-hybrid
Homo sapiens
36
MEI1
Affinity Capture-MS
Homo sapiens
37
KLHL24
Affinity Capture-MS
Homo sapiens
38
COPS6
10980
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
39
FZR1
Biochemical Activity
Homo sapiens
Reconstituted Complex
Homo sapiens
Biochemical Activity
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
40
PTPN4
Two-hybrid
Homo sapiens
41
GDI1
2664
Two-hybrid
Homo sapiens
42
ADD1
118
Two-hybrid
Homo sapiens
43
USP4
7375
Two-hybrid
Homo sapiens
44
DNAJB1
3337
Affinity Capture-MS
Homo sapiens
45
TTC38
55020
Two-hybrid
Homo sapiens
46
KDM6B
23135
Two-hybrid
Homo sapiens
47
CHGB
1114
Two-hybrid
Homo sapiens
48
FAF1
11124
Two-hybrid
Homo sapiens
49
CRMP1
1400
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
50
PLA2G10
Affinity Capture-MS
Homo sapiens
51
SMC5
23137
Two-hybrid
Homo sapiens
52
ZNF202
Affinity Capture-MS
Homo sapiens
53
MPP1
4354
Two-hybrid
Homo sapiens
54
WIZ
58525
Two-hybrid
Homo sapiens
55
METTL23
Two-hybrid
Homo sapiens
56
HMGXB3
Two-hybrid
Homo sapiens
57
HSPBAP1
Two-hybrid
Homo sapiens
58
FAM20C
56975
Two-hybrid
Homo sapiens
59
EEF1A1
1915
Two-hybrid
Homo sapiens
60
DVL2
1856
Affinity Capture-MS
Homo sapiens
61
MSH2
4436
Two-hybrid
Homo sapiens
62
BAG6
7917
Two-hybrid
Homo sapiens
63
DUS2
54920
Two-hybrid
Homo sapiens
64
ABHD4
63874
Two-hybrid
Homo sapiens
65
AGAP1
Two-hybrid
Homo sapiens
66
C19orf60
Two-hybrid
Homo sapiens
67
ALAS1
Two-hybrid
Homo sapiens
68
SEZ6L2
26470
Two-hybrid
Homo sapiens
69
PROC
5624
Two-hybrid
Homo sapiens
70
ODC1
4953
Two-hybrid
Homo sapiens
71
CDKN1A
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
72
WDR73
Two-hybrid
Homo sapiens
73
ZBTB16
Two-hybrid
Homo sapiens
74
PSME1
5720
Two-hybrid
Homo sapiens
75
A2M
2
Two-hybrid
Homo sapiens
76
TUBA1A
7846
Two-hybrid
Homo sapiens
77
LRIF1
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
78
MPPED1
Two-hybrid
Homo sapiens
79
ASNA1
439
Two-hybrid
Homo sapiens
80
KIF5A
3798
Two-hybrid
Homo sapiens
81
SP110
Two-hybrid
Homo sapiens
82
DRAP1
10589
Two-hybrid
Homo sapiens
83
NGFR
4804
Two-hybrid
Homo sapiens
84
ZNF131
Affinity Capture-MS
Homo sapiens
85
MOV10
4343
Affinity Capture-RNA
Homo sapiens
86
NCS1
23413
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
87
UNC119
9094
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
88
ACTB
60
Two-hybrid
Homo sapiens
89
EZH2
Two-hybrid
Homo sapiens
90
PLXNA3
55558
Two-hybrid
Homo sapiens
91
MED31
Two-hybrid
Homo sapiens
92
SDF4
51150
Two-hybrid
Homo sapiens
93
ATP5B
506
Two-hybrid
Homo sapiens
94
ARFGAP1
55738
Two-hybrid
Homo sapiens
95
NKIRAS2
Two-hybrid
Homo sapiens
96
SEPT6
23157
Two-hybrid
Homo sapiens
97
TYK2
7297
Two-hybrid
Homo sapiens
98
EIF4A2
1974
Two-hybrid
Homo sapiens
99
DDAH2
23564
Two-hybrid
Homo sapiens
100
SEMA5B
Two-hybrid
Homo sapiens
101
SNX1
6642
Two-hybrid
Homo sapiens
102
CCDC115
84317
Two-hybrid
Homo sapiens
103
EIF3G
8666
Two-hybrid
Homo sapiens
104
COL4A2
1284
Two-hybrid
Homo sapiens
105
HADHB
3032
Two-hybrid
Homo sapiens
106
C14orf1
11161
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
107
RPL13
6137
Two-hybrid
Homo sapiens
108
EIF6
3692
Two-hybrid
Homo sapiens
109
DOCK7
85440
Two-hybrid
Homo sapiens
110
ZNF232
Affinity Capture-MS
Homo sapiens
111
ADAMTS10
81794
Two-hybrid
Homo sapiens
112
CRYAB
1410
Affinity Capture-MS
Homo sapiens
113
CUL3
8452
Affinity Capture-MS
Homo sapiens
114
DCAF13
25879
Two-hybrid
Homo sapiens
115
RBBP4
5928
Two-hybrid
Homo sapiens
116
PM20D2
135293
Affinity Capture-MS
Homo sapiens
117
FN1
2335
Affinity Capture-MS
Homo sapiens
118
KIF21B
23046
Two-hybrid
Homo sapiens
119
INPP5K
51763
Two-hybrid
Homo sapiens
120
NRBP1
29959
Two-hybrid
Homo sapiens
121
GPCPD1
Two-hybrid
Homo sapiens
122
EDA2R
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
123
RPA3
6119
Proximity Label-MS
Homo sapiens
124
KLHL5
Two-hybrid
Homo sapiens
125
COL4A5
Two-hybrid
Homo sapiens
126
MAGEA4
4103
Two-hybrid
Homo sapiens
127
MRFAP1
Two-hybrid
Homo sapiens
128
NMT2
9397
Two-hybrid
Homo sapiens
129
ACTL6B
Two-hybrid
Homo sapiens
130
CARHSP1
23589
Two-hybrid
Homo sapiens
131
LOC148413
Two-hybrid
Homo sapiens
132
NEUROD2
Two-hybrid
Homo sapiens
133
F13A1
2162
Two-hybrid
Homo sapiens
134
CPSF3L
54973
Two-hybrid
Homo sapiens
135
UPF2
26019
Two-hybrid
Homo sapiens
136
TIAM2
26230
Two-hybrid
Homo sapiens
137
KCNMB2
Affinity Capture-MS
Homo sapiens
138
TCTEX1D2
Two-hybrid
Homo sapiens
139
IMMT
10989
Two-hybrid
Homo sapiens
140
TRIM46
80128
Two-hybrid
Homo sapiens
141
TUBB2A
7280
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
142
DALRD3
Two-hybrid
Homo sapiens
143
PLEKHA4
57664
Affinity Capture-MS
Homo sapiens
144
PPP4C
5531
Two-hybrid
Homo sapiens
145
CSAD
51380
Two-hybrid
Homo sapiens
146
CDC20
991
Reconstituted Complex
Homo sapiens
147
ITSN1
6453
Two-hybrid
Homo sapiens
148
ATXN3
4287
Two-hybrid
Homo sapiens
149
TP53
7157
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
150
THOC3
Two-hybrid
Homo sapiens
151
DEAF1
10522
Two-hybrid
Homo sapiens
152
KMT2B
Two-hybrid
Homo sapiens
153
ATG16L2
Two-hybrid
Homo sapiens
154
CRIP1
1396
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
155
IER3IP1
51124
Two-hybrid
Homo sapiens
156
RPA1
6117
Two-hybrid
Homo sapiens
157
TLE1
7088
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
158
TRMT2A
27037
Two-hybrid
Homo sapiens
159
FGB
2244
Two-hybrid
Homo sapiens
160
TUBB3
10381
Two-hybrid
Homo sapiens
161
SQSTM1
8878
Proximity Label-MS
Homo sapiens
162
ACTR1B
10120
Two-hybrid
Homo sapiens
163
MAMDC2
256691
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
164
PAAF1
80227
Two-hybrid
Homo sapiens
165
MKI67
Two-hybrid
Homo sapiens
166
WDR18
57418
Two-hybrid
Homo sapiens
167
FST
10468
Two-hybrid
Homo sapiens
168
IGLL5
100423062
Affinity Capture-MS
Homo sapiens
169
MAST2
Two-hybrid
Homo sapiens
170
SULT1A3
6818
Two-hybrid
Homo sapiens
171
CRIP2
1397
Two-hybrid
Homo sapiens
172
PLD3
23646
Two-hybrid
Homo sapiens
173
BTBD1
Affinity Capture-MS
Homo sapiens
174
GAPDH
2597
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
175
EXT2
2132
Two-hybrid
Homo sapiens
176
DMPK
Two-hybrid
Homo sapiens
177
LRRK2
120892
Affinity Capture-MS
Homo sapiens
178
CDK4
1019
Two-hybrid
Homo sapiens
179
RXRA
6256
Two-hybrid
Homo sapiens
180
HERC3
8916
Two-hybrid
Homo sapiens
181
TAF1C
Two-hybrid
Homo sapiens
182
PTPRK
5796
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
183
PDE4DIP
9659
Two-hybrid
Homo sapiens
184
CUL7
9820
Affinity Capture-MS
Homo sapiens
185
TMSB4X
7114
Two-hybrid
Homo sapiens
186
SUMO3
6612
Two-hybrid
Homo sapiens
187
ZNF431
Two-hybrid
Homo sapiens
188
AAMP
14
Two-hybrid
Homo sapiens
189
FLAD1
80308
Two-hybrid
Homo sapiens
190
WDR60
55112
Two-hybrid
Homo sapiens
191
AGRP
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which TK1 is involved