Gene description for MTCH2
Gene name mitochondrial carrier 2
Gene symbol MTCH2
Other names/aliases HSPC032
MIMP
SLC25A50
Species Homo sapiens
 Database cross references - MTCH2
ExoCarta ExoCarta_23788
Vesiclepedia VP_23788
Entrez Gene 23788
HGNC 17587
MIM 613221
UniProt Q9Y6C9  
 MTCH2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 17956143    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
 Gene ontology annotations for MTCH2
Molecular Function
    protein binding GO:0005515 IPI
    membrane insertase activity GO:0032977 IDA
Biological Process
    regulation of mitochondrial fusion GO:0010635 ISS
    positive regulation of apoptotic process GO:0043065 IBA
    positive regulation of apoptotic process GO:0043065 ISS
    protein insertion into mitochondrial outer membrane GO:0045040 IDA
    lipid homeostasis GO:0055088 ISS
    protein localization to mitochondrion GO:0070585 IMP
    positive regulation of stem cell differentiation GO:2000738 ISS
Subcellular Localization
    nucleus GO:0005634 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrial outer membrane GO:0005741 IDA
    membrane GO:0016020 HDA
    membrane GO:0016020 IBA
 Experiment description of studies that identified MTCH2 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
10
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
19
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for MTCH2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ARHGAP1 392
Proximity Label-MS Homo sapiens
2 WDR6 11180
Proximity Label-MS Homo sapiens
3 FAM73A  
Proximity Label-MS Homo sapiens
4 DNAJC11 55735
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
5 NPRL2  
Affinity Capture-MS Homo sapiens
6 NRSN1  
Affinity Capture-MS Homo sapiens
7 UBC 7316
Affinity Capture-MS Homo sapiens
8 FAM219B 57184
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 CKB 1152
Proximity Label-MS Homo sapiens
10 MAP1LC3B 81631
Affinity Capture-Western Homo sapiens
11 GFPT1 2673
Affinity Capture-MS Homo sapiens
12 COX7A2L 9167
Co-fractionation Homo sapiens
13 ARMCX4  
Proximity Label-MS Homo sapiens
14 STOM 2040
Co-fractionation Homo sapiens
15 CLEC2B  
Affinity Capture-MS Homo sapiens
16 CHCHD10  
Affinity Capture-MS Homo sapiens
17 HSPH1 10808
Affinity Capture-MS Homo sapiens
18 ABCD3 5825
Proximity Label-MS Homo sapiens
19 ETFA 2108
Proximity Label-MS Homo sapiens
20 ARMCX3 51566
Proximity Label-MS Homo sapiens
21 VPS13D 55187
Proximity Label-MS Homo sapiens
22 RHOA 387
Proximity Label-MS Homo sapiens
23 SLC25A46 91137
Proximity Label-MS Homo sapiens
24 HYPM  
Affinity Capture-MS Homo sapiens
25 MECP2 4204
Affinity Capture-MS Homo sapiens
26 NSFL1C 55968
Proximity Label-MS Homo sapiens
27 SLC25A3 5250
Co-fractionation Homo sapiens
28 KIF14 9928
Affinity Capture-MS Homo sapiens
29 BAG5 9529
Proximity Label-MS Homo sapiens
30 MTFR1L 56181
Proximity Label-MS Homo sapiens
31 UBXN8  
Affinity Capture-MS Homo sapiens
32 RFX3 5991
Affinity Capture-MS Homo sapiens
33 RPL31 6160
Affinity Capture-MS Homo sapiens
34 SYNE1 23345
Proximity Label-MS Homo sapiens
35 RMDN2 151393
Proximity Label-MS Homo sapiens
36 CYC1 1537
Co-fractionation Homo sapiens
37 TNFRSF10C  
Affinity Capture-MS Homo sapiens
38 VDAC2 7417
Co-fractionation Homo sapiens
39 ADCK1  
Affinity Capture-MS Homo sapiens
40 ANLN 54443
Affinity Capture-MS Homo sapiens
41 CISD1 55847
Proximity Label-MS Homo sapiens
42 SDHC 6391
Co-fractionation Homo sapiens
43 HSPA5 3309
Affinity Capture-MS Homo sapiens
44 RBM39 9584
Affinity Capture-MS Homo sapiens
45 HADHB 3032
Co-fractionation Homo sapiens
46 HADHA 3030
Co-fractionation Homo sapiens
47 CDCA3 83461
Proximity Label-MS Homo sapiens
48 UBQLN2 29978
Proximity Label-MS Homo sapiens
49 BCAP31 10134
Co-fractionation Homo sapiens
50 RAB29 8934
Proximity Label-MS Homo sapiens
51 ASS1 445
Affinity Capture-MS Homo sapiens
52 GPD2 2820
Proximity Label-MS Homo sapiens
53 FKBP8 23770
Proximity Label-MS Homo sapiens
54 MYO19  
Proximity Label-MS Homo sapiens
55 AAAS 8086
Proximity Label-MS Homo sapiens
56 ATP1B3 483
Co-fractionation Homo sapiens
57 ZNF782  
Co-fractionation Homo sapiens
58 FARSB 10056
Affinity Capture-MS Homo sapiens
59 PCBP1 5093
Affinity Capture-MS Homo sapiens
60 RPA3 6119
Proximity Label-MS Homo sapiens
61 COX6C 1345
Co-fractionation Homo sapiens
62 PLIN3 10226
Affinity Capture-MS Homo sapiens
63 PVR 5817
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 DUSP21  
Affinity Capture-MS Homo sapiens
65 CRYBG3  
Proximity Label-MS Homo sapiens
66 SCCPDH 51097
Co-fractionation Homo sapiens
67 STUB1 10273
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
68 HK2 3099
Proximity Label-MS Homo sapiens
69 MIEF1  
Proximity Label-MS Homo sapiens
70 PPT1 5538
Affinity Capture-MS Homo sapiens
71 CHML  
Proximity Label-MS Homo sapiens
72 SCYL3 57147
Affinity Capture-MS Homo sapiens
73 RUVBL2 10856
Affinity Capture-MS Homo sapiens
74 VAC14 55697
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 COX5A 9377
Co-fractionation Homo sapiens
76 PRKCH 5583
Proximity Label-MS Homo sapiens
77 NUDT19 390916
Proximity Label-MS Homo sapiens
78 WIF1 11197
Affinity Capture-MS Homo sapiens
79 ATAD3A 55210
Proximity Label-MS Homo sapiens
80 PTPN5  
Affinity Capture-MS Homo sapiens
81 TEX264 51368
Affinity Capture-MS Homo sapiens
82 MIEF2  
Proximity Label-MS Homo sapiens
83 PCCB 5096
Co-fractionation Homo sapiens
84 HSDL1 83693
Proximity Label-MS Homo sapiens
85 DUSP4 1846
Affinity Capture-MS Homo sapiens
86 CISD2 493856
Proximity Label-MS Homo sapiens
87 ADGRE5 976
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 ST13 6767
Proximity Label-MS Homo sapiens
89 PLD6  
Proximity Label-MS Homo sapiens
90 ARMC10 83787
Proximity Label-MS Homo sapiens
91 SNAP29 9342
Proximity Label-MS Homo sapiens
92 PDHA1 5160
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
93 PSME2 5721
Affinity Capture-MS Homo sapiens
94 AFG3L2 10939
Proximity Label-MS Homo sapiens
95 DDHD2 23259
Proximity Label-MS Homo sapiens
96 MARCH2  
Proximity Label-MS Homo sapiens
97 TMEM206 55248
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 NUDCD3 23386
Proximity Label-MS Homo sapiens
99 NDUFB5 4711
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
100 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
101 HSPB1 3315
Affinity Capture-MS Homo sapiens
102 CAND1 55832
Affinity Capture-MS Homo sapiens
103 HSPA4L 22824
Proximity Label-MS Homo sapiens
104 NDUFA4 4697
Affinity Capture-MS Homo sapiens
105 CPT1A 1374
Co-fractionation Homo sapiens
106 ATP5L 10632
Co-fractionation Homo sapiens
107 HCCS 3052
Affinity Capture-MS Homo sapiens
108 PRR11  
Proximity Label-MS Homo sapiens
109 B3GNT2 10678
Affinity Capture-MS Homo sapiens
110 OGDH 4967
Co-fractionation Homo sapiens
111 WDR41  
Proximity Label-MS Homo sapiens
112 TUBB 203068
Affinity Capture-MS Homo sapiens
113 COQ9  
Affinity Capture-MS Homo sapiens
114 TRABD 80305
Proximity Label-MS Homo sapiens
115 PRC1 9055
Affinity Capture-MS Homo sapiens
116 NDUFA5 4698
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
117 STIP1 10963
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
118 VAPB 9217
Co-fractionation Homo sapiens
119 DNAJC7 7266
Proximity Label-MS Homo sapiens
120 PHB 5245
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
121 TOMM40 10452
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
122 ANKRD34C  
Co-fractionation Homo sapiens
123 HK1 3098
Proximity Label-MS Homo sapiens
124 TDRKH  
Proximity Label-MS Homo sapiens
125 LMAN1 3998
Co-fractionation Homo sapiens
126 NDUFB1 4707
Co-fractionation Homo sapiens
127 TTC37 9652
Proximity Label-MS Homo sapiens
128 CHMP7 91782
Proximity Label-MS Homo sapiens
129 SLC1A5 6510
Affinity Capture-MS Homo sapiens
130 FUNDC2 65991
Proximity Label-MS Homo sapiens
131 NDUFA8 4702
Co-fractionation Homo sapiens
132 ATPAF1  
Proximity Label-MS Homo sapiens
133 BAG6 7917
Proximity Label-MS Homo sapiens
134 SNAP47 116841
Proximity Label-MS Homo sapiens
135 GK  
Proximity Label-MS Homo sapiens
136 NME3 4832
Proximity Label-MS Homo sapiens
137 UQCRC1 7384
Co-fractionation Homo sapiens
138 MAOA 4128
Proximity Label-MS Homo sapiens
139 UPK1A 11045
Affinity Capture-MS Homo sapiens
140 GET4 51608
Proximity Label-MS Homo sapiens
141 ABCB7 22
Proximity Label-MS Homo sapiens
142 FBXL4 26235
Proximity Label-MS Homo sapiens
143 SUCNR1 56670
Affinity Capture-MS Homo sapiens
144 C15orf48  
Affinity Capture-MS Homo sapiens
145 SGPL1 8879
Co-fractionation Homo sapiens
146 FLNA 2316
Affinity Capture-MS Homo sapiens
147 MTX2 10651
Proximity Label-MS Homo sapiens
148 PRKAR2A 5576
Proximity Label-MS Homo sapiens
149 ATP5F1 515
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
150 MTFR1  
Proximity Label-MS Homo sapiens
151 MTFR2  
Proximity Label-MS Homo sapiens
152 TOMM70A 9868
Proximity Label-MS Homo sapiens
153 RPS27 6232
Affinity Capture-MS Homo sapiens
154 ARHGAP25  
Affinity Capture-MS Homo sapiens
155 ACAD9 28976
Proximity Label-MS Homo sapiens
156 DDB1 1642
Proximity Label-MS Homo sapiens
157 DDRGK1 65992
Affinity Capture-MS Homo sapiens
158 BNIP3 664
Proximity Label-MS Homo sapiens
159 ARGLU1  
Proximity Label-MS Homo sapiens
160 FHL2 2274
Affinity Capture-MS Homo sapiens
161 LARP4 113251
Proximity Label-MS Homo sapiens
162 GEMIN4 50628
Proximity Label-MS Homo sapiens
163 CLPP 8192
Proximity Label-MS Homo sapiens
164 TTC1 7265
Proximity Label-MS Homo sapiens
165 FAF2 23197
Proximity Label-MS Homo sapiens
166 PDCL 5082
Proximity Label-MS Homo sapiens
167 SPIRE1 56907
Proximity Label-MS Homo sapiens
168 BCKDHA 593
Co-fractionation Homo sapiens
169 BID  
Affinity Capture-Western Homo sapiens
170 CENPF 1063
Proximity Label-MS Homo sapiens
171 FKBP4 2288
Proximity Label-MS Homo sapiens
172 TSC1 7248
Proximity Label-MS Homo sapiens
173 PRKAR2B 5577
Proximity Label-MS Homo sapiens
174 ESR1  
Two-hybrid Homo sapiens
175 BCL2L13 23786
Proximity Label-MS Homo sapiens
176 BCL2L1 598
Affinity Capture-MS Homo sapiens
177 TECTB  
Affinity Capture-MS Homo sapiens
178 SPPL2B 56928
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
179 ATP1A1 476
Co-fractionation Homo sapiens
180 YKT6 10652
Proximity Label-MS Homo sapiens
181 KIR2DL4  
Affinity Capture-MS Homo sapiens
182 KRAS 3845
Affinity Capture-MS Homo sapiens
183 C14orf2  
Two-hybrid Homo sapiens
184 TOMM5  
Co-fractionation Homo sapiens
185 ATP6V1B2 526
Co-fractionation Homo sapiens
186 LYPD3 27076
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 RAB1A 5861
Co-fractionation Homo sapiens
188 NDUFS1 4719
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
189 GLP1R  
PCA Homo sapiens
190 SLC38A6  
Affinity Capture-MS Homo sapiens
191 PTPN1 5770
Proximity Label-MS Homo sapiens
192 NDUFB9 4715
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
193 MGST1 4257
Co-fractionation Homo sapiens
194 NDUFS3 4722
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
195 YWHAZ 7534
Affinity Capture-MS Homo sapiens
196 NDUFB8 4714
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
197 MCM2 4171
Affinity Capture-MS Homo sapiens
198 SDHB 6390
Co-fractionation Homo sapiens
199 PTPMT1 114971
Affinity Capture-MS Homo sapiens
200 TIMMDC1  
Proximity Label-MS Homo sapiens
201 RAB3B 5865
Proximity Label-MS Homo sapiens
202 CALCOCO2  
Affinity Capture-MS Homo sapiens
203 EWSR1 2130
Affinity Capture-MS Homo sapiens
204 C20orf24  
Co-fractionation Homo sapiens
205 NDUFV1 4723
Co-fractionation Homo sapiens
206 RHOT1 55288
Proximity Label-MS Homo sapiens
207 MAVS 57506
Proximity Label-MS Homo sapiens
208 UQCRQ 27089
Co-fractionation Homo sapiens
209 NDUFS5 4725
Co-fractionation Homo sapiens
210 HSPA8 3312
Affinity Capture-MS Homo sapiens
211 INSIG2  
Affinity Capture-MS Homo sapiens
212 PALD1 27143
Proximity Label-MS Homo sapiens
213 ATAD3B 83858
Proximity Label-MS Homo sapiens
214 ATP5A1 498
Co-fractionation Homo sapiens
215 SAMM50 25813
Proximity Label-MS Homo sapiens
216 PARK2  
Affinity Capture-MS Homo sapiens
217 CHCHD3 54927
Proximity Label-MS Homo sapiens
218 XRN1 54464
Two-hybrid Homo sapiens
219 PAM16  
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
220 NTRK1 4914
Affinity Capture-MS Homo sapiens
221 TGFA  
Affinity Capture-MS Homo sapiens
222 ATP5C1 509
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
223 DNAJA1 3301
Proximity Label-MS Homo sapiens
224 TACC1 6867
Proximity Label-MS Homo sapiens
225 ACTB 60
Co-fractionation Homo sapiens
226 GNAI2 2771
Co-fractionation Homo sapiens
227 TSPAN31 6302
Affinity Capture-MS Homo sapiens
228 NUDC 10726
Proximity Label-MS Homo sapiens
229 MFF 56947
Proximity Label-MS Homo sapiens
230 DNM1L 10059
Proximity Label-MS Homo sapiens
231 FAM73B  
Proximity Label-MS Homo sapiens
232 RMDN3 55177
Proximity Label-MS Homo sapiens
233 DUSP22  
Affinity Capture-MS Homo sapiens
234 ZBTB2 57621
Affinity Capture-MS Homo sapiens
235 SMCR8 140775
Proximity Label-MS Homo sapiens
236 SLC25A12 8604
Proximity Label-MS Homo sapiens
237 MINOS1  
Co-fractionation Homo sapiens
238 BAG2 9532
Proximity Label-MS Homo sapiens
239 ECT2 1894
Affinity Capture-MS Homo sapiens
240 SARM1 23098
Proximity Label-MS Homo sapiens
241 LMNB2 84823
Proximity Label-MS Homo sapiens
242 GPAM 57678
Proximity Label-MS Homo sapiens
243 FBXO6 26270
Affinity Capture-MS Homo sapiens
244 CORO1C 23603
Co-fractionation Homo sapiens
245 OCIAD1 54940
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
246 AMY1C 278
Affinity Capture-MS Homo sapiens
247 NEFL 4747
Proximity Label-MS Homo sapiens
248 EMC2 9694
Co-fractionation Homo sapiens
249 RPN1 6184
Co-fractionation Homo sapiens
250 RNF2  
Affinity Capture-MS Homo sapiens
251 ZC3HAV1 56829
Proximity Label-MS Homo sapiens
252 SEPT7 989
Affinity Capture-MS Homo sapiens
253 HAX1  
Proximity Label-MS Homo sapiens
254 HSPD1 3329
Affinity Capture-MS Homo sapiens
255 AKAP1 8165
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
256 UBXN4 23190
Proximity Label-MS Homo sapiens
257 NDUFS2 4720
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
258 TSPAN10 83882
Affinity Capture-MS Homo sapiens
259 IMMT 10989
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
260 SUGT1 10910
Proximity Label-MS Homo sapiens
261 PHB2 11331
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
262 ALDH3A2 224
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
263 FBXL6  
Affinity Capture-MS Homo sapiens
264 RPL6 6128
Affinity Capture-MS Homo sapiens
265 OPALIN  
Affinity Capture-MS Homo sapiens
266 WNT4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
267 APOC1  
Two-hybrid Homo sapiens
268 NDUFA12 55967
Co-fractionation Homo sapiens
269 DDX58 23586
Affinity Capture-RNA Homo sapiens
270 UFL1 23376
Affinity Capture-MS Homo sapiens
271 NDUFS8 4728
Co-fractionation Homo sapiens
272 NDUFA2 4695
Co-fractionation Homo sapiens
273 INF2 64423
Proximity Label-MS Homo sapiens
274 RAB7A 7879
Proximity Label-MS Homo sapiens
275 CIT 11113
Affinity Capture-MS Homo sapiens
276 CORO1B 57175
Affinity Capture-MS Homo sapiens
277 TNFRSF13C  
Affinity Capture-MS Homo sapiens
278 COX7C 1350
Co-fractionation Homo sapiens
279 CD44 960
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
280 VDAC3 7419
Co-fractionation Homo sapiens
281 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
282 INSIG1  
Affinity Capture-MS Homo sapiens
283 FMNL1 752
Affinity Capture-MS Homo sapiens
284 BCLAF1 9774
Affinity Capture-MS Homo sapiens
285 HCST  
Affinity Capture-MS Homo sapiens
286 ERAP2 64167
Affinity Capture-MS Homo sapiens
287 VPS13A 23230
Proximity Label-MS Homo sapiens
288 HSD17B3  
Affinity Capture-MS Homo sapiens
289 MRPL37 51253
Co-fractionation Homo sapiens
290 BNIP3L  
Proximity Label-MS Homo sapiens
291 BCAM 4059
Affinity Capture-MS Homo sapiens
292 TOMM22 56993
Co-fractionation Homo sapiens
293 KIAA1429 25962
Affinity Capture-MS Homo sapiens
294 DGKH 160851
Proximity Label-MS Homo sapiens
295 CYB5R1 51706
Proximity Label-MS Homo sapiens
296 COA3 28958
Co-fractionation Homo sapiens
297 ATP5O 539
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
298 PGRMC2 10424
Proximity Label-MS Homo sapiens
299 SERPINH1 871
Affinity Capture-MS Homo sapiens
300 EXD2  
Proximity Label-MS Homo sapiens
301 VAT1 10493
Proximity Label-MS Homo sapiens
302 ATP6V0D1 9114
Co-fractionation Homo sapiens
303 ATP5H 10476
Co-fractionation Homo sapiens
304 PPP1R15B  
Proximity Label-MS Homo sapiens
305 NDUFA6  
Co-fractionation Homo sapiens
306 SARS 6301
Affinity Capture-MS Homo sapiens
307 RIC3  
Affinity Capture-MS Homo sapiens
308 LAMTOR1 55004
Affinity Capture-MS Homo sapiens
309 ADSL 158
Affinity Capture-MS Homo sapiens
310 IMPDH1 3614
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
311 TBC1D17 79735
Proximity Label-MS Homo sapiens
312 E2F4  
Affinity Capture-MS Homo sapiens
313 CYB5A 1528
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
314 APOL2 23780
Proximity Label-MS Homo sapiens
315 DDX5 1655
Affinity Capture-MS Homo sapiens
316 MLX  
Proximity Label-MS Homo sapiens
317 PML 5371
Affinity Capture-MS Homo sapiens
318 DNM2 1785
Affinity Capture-MS Homo sapiens
319 RHOT2 89941
Proximity Label-MS Homo sapiens
320 DUSP23 54935
Affinity Capture-MS Homo sapiens
321 NIPSNAP1 8508
Co-fractionation Homo sapiens
322 ATP5B 506
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
323 SLC7A1 6541
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
324 ACBD3 64746
Proximity Label-MS Homo sapiens
325 COX4I1 1327
Co-fractionation Homo sapiens
326 OXA1L  
Affinity Capture-MS Homo sapiens
327 CYB5B 80777
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
328 GOLGA3 2802
Proximity Label-MS Homo sapiens
329 FANCD2  
Affinity Capture-MS Homo sapiens
330 NDUFB10 4716
Co-fractionation Homo sapiens
331 MARCH1  
Proximity Label-MS Homo sapiens
332 NDUFA9 4704
Co-fractionation Homo sapiens
333 UQCRC2 7385
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
334 CACNG2  
Affinity Capture-MS Homo sapiens
335 RPL7 6129
Affinity Capture-MS Homo sapiens
336 EHBP1 23301
Proximity Label-MS Homo sapiens
337 PRKACA 5566
Proximity Label-MS Homo sapiens
338 MAPK6  
Affinity Capture-MS Homo sapiens
339 APOOL 139322
Affinity Capture-MS Homo sapiens
340 TSPAN1 10103
Affinity Capture-MS Homo sapiens
341 ATP6V1A 523
Co-fractionation Homo sapiens
342 ATP1B1 481
Co-fractionation Homo sapiens
343 SIRT2 22933
Proximity Label-MS Homo sapiens
344 STBD1 8987
Proximity Label-MS Homo sapiens
345 VDAC1 7416
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
346 CLTC 1213
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
347 FSCN1 6624
Affinity Capture-MS Homo sapiens
348 NDUFC2 4718
Co-fractionation Homo sapiens
349 C9orf72  
Proximity Label-MS Homo sapiens
350 RRBP1 6238
Proximity Label-MS Homo sapiens
351 TRAK1 22906
Proximity Label-MS Homo sapiens
352 SYAP1 94056
Proximity Label-MS Homo sapiens
353 INPPL1 3636
Affinity Capture-MS Homo sapiens
354 DNAJA2 10294
Proximity Label-MS Homo sapiens
355 UBA52 7311
Affinity Capture-MS Homo sapiens
356 NDUFS7 374291
Co-fractionation Homo sapiens
357 PDHB 5162
Co-fractionation Homo sapiens
358 OPA3 80207
Affinity Capture-MS Homo sapiens
359 ATP2A2 488
Co-fractionation Homo sapiens
360 UBB 7314
Proximity Label-MS Homo sapiens
361 USP30  
Proximity Label-MS Homo sapiens
362 MOV10 4343
Proximity Label-MS Homo sapiens
363 PEX5 5830
Proximity Label-MS Homo sapiens
364 HNRNPU 3192
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
365 MTX3  
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which MTCH2 is involved
No pathways found





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