Experiment description of studies that identified SLC9A3R1 in sEVs

1 Experiment ID 79 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20458337     Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W." Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting

2 Experiment ID 80 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20458337     Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W." Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting

3 Experiment ID 81 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20458337     Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W." Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting

4 Experiment ID 76 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20224111     Organism Homo sapiens Experiment description Proteomics analysis of bladder cancer exosomes. Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A." Journal name MCP Publication year 2010 Sample Bladder cancer cells Sample name HT1376 Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.10-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [MALDI TOF/TOF] Western blotting FACS

5 Experiment ID 489 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Rattus norvegicus Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Bone marrow mesenchymal stem cells Sample name BMSC - Passage 6 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

6 Experiment ID 490 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Rattus norvegicus Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Bone marrow mesenchymal stem cells Sample name BMSC - Passage 7 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

7 Experiment ID 491 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Rattus norvegicus Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Bone marrow mesenchymal stem cells Sample name BMSC - Passage 8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

8 Experiment ID 492 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Rattus norvegicus Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Bone marrow mesenchymal stem cells Sample name BMSC - Passage 9 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

9 Experiment ID 412 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

10 Experiment ID 414 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

11 Experiment ID 426 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

12 Experiment ID 427 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

13 Experiment ID 20 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 17956143     Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells. Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS" Journal name JPR Publication year 2007 Sample Colorectal cancer cells Sample name HT29 Isolation/purification methods Differential centrifugation Sucrose density gradient Diafiltration Flotation density 1.16 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting

14 Experiment ID 286 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✔ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25890246     Organism Homo sapiens Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct. Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ." Journal name Methods Publication year 2015 Sample Colorectal cancer cells Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2 Isolation/purification methods Differential centrifugation Filtration Sequential centrifugal ultrafiltration Centrifugal concentration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

15 Experiment ID 407 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Embryonic kidney cells Sample name HEK293T Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

16 Experiment ID 419 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Embryonic kidney cells Sample name HEK293T - Exo-rich fractions 7-10 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

17 Experiment ID 419 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Embryonic kidney cells Sample name HEK293T - Exo-rich fractions 7-10 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

18 Experiment ID 420 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Embryonic kidney cells Sample name HEK293T - Exo-rich fractions 1-6 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

19 Experiment ID 420 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Embryonic kidney cells Sample name HEK293T - Exo-rich fractions 1-6 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

20 Experiment ID 1275 MISEV standards Biophysical techniques ✔ Enriched markers ✔ Negative markers Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36706192     Organism Homo sapiens Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q." Journal name Sci Adv Publication year 2023 Sample Embryonic kidney cells Sample name HEK293T Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

21 Experiment ID 1280 MISEV standards Biophysical techniques ✔ Enriched markers ✔ Negative markers Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36706192     Organism Homo sapiens Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q." Journal name Sci Adv Publication year 2023 Sample Embryonic kidney cells Sample name HEK293T - Fraction 5 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation Flotation density 1.151 g/mL Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

22 Experiment ID 405 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Foreskin fibroblasts Sample name BJ Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

23 Experiment ID 363 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33991177     Organism Homo sapiens Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." Journal name Proteomics Publication year 2021 Sample Gastric cancer cells Sample name MKN1 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

24 Experiment ID 364 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33991177     Organism Homo sapiens Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." Journal name Proteomics Publication year 2021 Sample Gastric cancer cells Sample name MKN1 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

25 Experiment ID 365 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33991177     Organism Homo sapiens Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." Journal name Proteomics Publication year 2021 Sample Gastric cancer cells Sample name MKN1 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

26 Experiment ID 234 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-C3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

27 Experiment ID 236 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

28 Experiment ID 237 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

29 Experiment ID 417 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Lymphoma cells Sample name Raji Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

30 Experiment ID 411 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Mammary cancer-associated fibroblasts Sample name mCAF Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

31 Experiment ID 418 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Monocytic leukemia cells Sample name THP-1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

32 Experiment ID 413 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Normal mammary epithelial cells Sample name MCF10A Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

33 Experiment ID 211 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

34 Experiment ID 212 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

35 Experiment ID 406 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Pancreatic cancer cells Sample name BxPC3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

36 Experiment ID 415 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Pancreatic cancer cells Sample name PANC-1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

37 Experiment ID 434 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Pancreatic cancer cells Sample name PANC-1 - Exo-rich fractions 7-10 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

38 Experiment ID 435 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Pancreatic cancer cells Sample name PANC-1 - Exo-rich fractions 1-6 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

39 Experiment ID 408 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Pancreatic duct epithalial cells Sample name HPDE Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

40 Experiment ID 409 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Pancreatic duct epithalial cells Sample name HPNE Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

41 Experiment ID 231 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✔ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Lipids Methods used in the study Western blotting Mass spectrometry

42 Experiment ID 232 MISEV standards ✘ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 2 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

43 Experiment ID 233 MISEV standards ✘ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

44 Experiment ID 416 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample Pluripotent stem cells Sample name PSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

45 Experiment ID 275 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25844599     Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T." Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 - Docetaxel sensitive Isolation/purification methods Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry/Flow cytometry/Western blotting

46 Experiment ID 834 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

47 Experiment ID 835 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

48 Experiment ID 66 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 19199708     Organism Homo sapiens Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR" Journal name JPR Publication year 2009 Sample Saliva Sample name Saliva Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting Immunoelectron Microscopy

49 Experiment ID 410 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✔ Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 34108659     Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R." Journal name Nat Cell Biol Publication year 2021 Sample T lymphocytes Sample name Jurkat Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry

50 Experiment ID 217 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✔ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23844026     Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O." Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

51 Experiment ID 34 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting Mass spectrometry PubMed ID 19190083     Organism Homo sapiens Experiment description Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. Authors "Kesimer M, Scull M, Brighton B, Demaria G, Burns K, O'Neal W, Pickles RJ, Sheehan JK" Journal name FASEB Publication year 2009 Sample Tracheobronchial cells Sample name Tracheobronchial epithelial cells Isolation/purification methods Differential centrifugation Filtration Sucrose density gradient Flotation density 1.16 -1.18 g/mL Molecules identified in the study Protein mRNA Methods used in the study Mass spectrometry [QTOF] Western blotting Immunoelectron Microscopy FACS

52 Experiment ID 13 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 15326289     Organism Homo sapiens Experiment description Identification and proteomic profiling of exosomes in human urine. Authors "Pisitkun T, Shen RF, Knepper MA" Journal name PNAS Publication year 2004 Sample Urine Sample name Urine - Normal Isolation/purification methods Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LCQ DECA XP] Western blotting

53 Experiment ID 63 MISEV standards ✘ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 19056867     Organism Homo sapiens Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes. Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA" Journal name JASN Publication year 2009 Sample Urine Sample name Urine - Normal Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting

54 Experiment ID 196 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 22418980     Organism Homo sapiens Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G." Journal name Kidney Int Publication year 2012 Sample Urine Sample name Urine - Normal high density Isolation/purification methods Differential centrifugation Sucrose cushion Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

55 Experiment ID 197 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 22418980     Organism Homo sapiens Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G." Journal name Kidney Int Publication year 2012 Sample Urine Sample name Urine - Normal low density Isolation/purification methods Differential centrifugation Sucrose cushion Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for SLC9A3R1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 CDCA5   Affinity Capture-MS Homo sapiens 2 HSPD1 3329 Co-fractionation Homo sapiens 3 NPEPPS 9520 Co-fractionation Homo sapiens 4 UQCRFS1 7386 Co-fractionation Homo sapiens 5 TBC1D10A 83874 Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens 6 CDKN1B 1027 Affinity Capture-MS Homo sapiens 7 MARCKS 4082 Proximity Label-MS Homo sapiens 8 LDHB 3945 Co-fractionation Homo sapiens 9 YTHDF1 54915 Co-fractionation Homo sapiens 10 MCC 4163 Affinity Capture-MS Homo sapiens 11 MME 4311 Affinity Capture-MS Homo sapiens 12 ADRB2   Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens Co-crystal Structure Homo sapiens Affinity Capture-Western Homo sapiens 13 CSE1L 1434 Co-fractionation Homo sapiens 14 RPS3 6188 Co-fractionation Homo sapiens 15 CKB 1152 Co-fractionation Homo sapiens 16 NEK7 140609 Co-fractionation Homo sapiens 17 RPS6KA3 6197 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens 18 FTO 79068 Co-fractionation Homo sapiens 19 P2RY1   Reconstituted Complex Homo sapiens 20 SOSTDC1   Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 21 CDH2 1000 Co-fractionation Homo sapiens 22 YES1 7525 Reconstituted Complex Homo sapiens 23 Trpc4   Reconstituted Complex Mus musculus Affinity Capture-Western Mus musculus 24 MDH1 4190 Co-fractionation Homo sapiens 25 CRABP1   Two-hybrid Homo sapiens 26 SLC9A3R2 9351 Affinity Capture-MS Homo sapiens 27 ABCC2 1244 Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens Co-localization Homo sapiens 28 PLCB1 287026 Reconstituted Complex Bos taurus 29 ASNSD1   Affinity Capture-MS Homo sapiens 30 PLCB3 5331 Affinity Capture-MS Homo sapiens 31 PTH1R   Far Western Homo sapiens Affinity Capture-Western Homo sapiens 32 PDZK1 5174 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Co-fractionation Homo sapiens 33 SLC9A3 6550 Affinity Capture-Western Homo sapiens 34 GDA 9615 Co-fractionation Homo sapiens 35 PRPH2 5961 Affinity Capture-MS Homo sapiens 36 PODXL 5420 Affinity Capture-MS Homo sapiens 37 PLCB1 23236 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 38 YWHAB 7529 Co-fractionation Homo sapiens 39 MAPK1 5594 Co-fractionation Homo sapiens 40 HEXIM1 10614 Affinity Capture-MS Homo sapiens 41 PTPRQ   Affinity Capture-MS Homo sapiens 42 NF2 4771 Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 43 AP5S1   Affinity Capture-MS Homo sapiens 44 ATP5A1 498 Co-fractionation Homo sapiens 45 FOXC1   Affinity Capture-MS Homo sapiens 46 WDR45B 56270 Affinity Capture-MS Homo sapiens 47 OPRK1   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 48 TGM2 7052 Co-fractionation Homo sapiens 49 PDGFRB 5159 Far Western Homo sapiens Reconstituted Complex Homo sapiens Co-localization Homo sapiens Far Western Homo sapiens Affinity Capture-Western Homo sapiens 50 FAM65C 140876 Affinity Capture-MS Homo sapiens 51 CLCN3 1182 Reconstituted Complex Homo sapiens 52 MCAM 4162 Proximity Label-MS Homo sapiens 53 DHRS2 10202 Affinity Capture-MS Homo sapiens 54 PSMF1 9491 Affinity Capture-MS Homo sapiens 55 PAG1 55824 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Co-fractionation Homo sapiens Far Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 56 UBFD1 56061 Co-fractionation Homo sapiens 57 PABPC1 26986 Co-fractionation Homo sapiens 58 CDH1 999 Proximity Label-MS Homo sapiens 59 GIT1 28964 Affinity Capture-MS Homo sapiens 60 YAP1 10413 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 61 Rdx 19684 Co-crystal Structure Mus musculus 62 NTRK1 4914 Affinity Capture-MS Homo sapiens 63 U2AF2 11338 Affinity Capture-MS Homo sapiens 64 SLC4A8 9498 Reconstituted Complex Homo sapiens 65 NOS2   Reconstituted Complex Homo sapiens 66 TACC1 6867 Co-fractionation Homo sapiens 67 ARL15 54622 Affinity Capture-MS Homo sapiens 68 SNRNP27   Affinity Capture-MS Homo sapiens 69 SMS 6611 Co-fractionation Homo sapiens 70 CAPN1 823 Co-fractionation Homo sapiens 71 KCTD3   Affinity Capture-MS Homo sapiens 72 CEBPA   Protein-peptide Homo sapiens 73 KCTD2   Affinity Capture-MS Homo sapiens 74 ZBED1   Affinity Capture-MS Homo sapiens 75 ARHGAP17 55114 Affinity Capture-MS Homo sapiens 76 PHLPP1   Far Western Homo sapiens Far Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 77 CD40 958 Affinity Capture-MS Homo sapiens 78 PALM2   Co-fractionation Homo sapiens 79 OGT 8473 Reconstituted Complex Homo sapiens 80 KCNJ1   Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 81 SMEK2   Co-fractionation Homo sapiens 82 YWHAZ 7534 Co-fractionation Homo sapiens 83 CTNNB1 1499 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 84 SRSF1 6426 Affinity Capture-MS Homo sapiens 85 PDGFRA 5156 Far Western Homo sapiens Reconstituted Complex Homo sapiens Far Western Homo sapiens Affinity Capture-Western Homo sapiens 86 PHLPP2   Affinity Capture-MS Homo sapiens Far Western Homo sapiens Affinity Capture-MS Homo sapiens Far Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 87 INTS7   Affinity Capture-MS Homo sapiens 88 SKP2   Far Western Homo sapiens Affinity Capture-Western Homo sapiens Protein-peptide Homo sapiens 89 PTEN 5728 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Phenotypic Enhancement Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens 90 PDIA3 2923 Co-fractionation Homo sapiens 91 NANS 54187 Co-fractionation Homo sapiens 92 ECHS1 1892 Co-fractionation Homo sapiens 93 G6PD 2539 Co-fractionation Homo sapiens 94 GNA11 2767 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 95 YWHAQ 10971 Co-fractionation Homo sapiens 96 Trpc5   Reconstituted Complex Mus musculus 97 OTULIN 90268 Affinity Capture-MS Homo sapiens 98 RHOB 388 Proximity Label-MS Homo sapiens 99 RNASET2   Co-fractionation Homo sapiens 100 TKFC 26007 Co-fractionation Homo sapiens 101 PCYOX1 51449 Co-fractionation Homo sapiens 102 MSN 4478 Reconstituted Complex Homo sapiens 103 AKT1 207 Biochemical Activity Homo sapiens Affinity Capture-Western Homo sapiens 104 BAIAP2 10458 Affinity Capture-MS Homo sapiens 105 UQCRFS1P1   Co-fractionation Homo sapiens 106 PPME1 51400 Co-fractionation Homo sapiens 107 SHKBP1   Affinity Capture-MS Homo sapiens 108 LDHAL6B 92483 Co-fractionation Homo sapiens 109 IREB2 3658 Co-fractionation Homo sapiens 110 EZR 7430 Reconstituted Complex Homo sapiens Co-fractionation Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-Western Homo sapiens Co-fractionation Homo sapiens 111 ABCC4 10257 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 112 PODXL2 50512 Affinity Capture-MS Homo sapiens 113 BCL10   Two-hybrid Homo sapiens 114 DDX58 23586 Affinity Capture-RNA Homo sapiens 115 SCN4A   Protein-peptide Homo sapiens 116 RPL23 9349 Co-fractionation Homo sapiens 117 RAB11A 8766 Proximity Label-MS Homo sapiens 118 SLC9A3R1 9368 Reconstituted Complex Homo sapiens Far Western Homo sapiens Reconstituted Complex Homo sapiens Far Western Homo sapiens 119 TCF3   Affinity Capture-MS Homo sapiens 120 ACO2 50 Affinity Capture-MS Homo sapiens 121 GNB2L1 10399 Affinity Capture-Western Homo sapiens 122 CFTR 1080 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Protein-peptide Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens Protein-peptide Homo sapiens Reconstituted Complex Homo sapiens 123 CCNT1   Affinity Capture-MS Homo sapiens 124 KCTD5 54442 Affinity Capture-MS Homo sapiens 125 ZNF468   Two-hybrid Homo sapiens 126 CNDP2 55748 Co-fractionation Homo sapiens View the network

Pathways in which SLC9A3R1 is involved

No pathways found