Experiment description of studies that identified LRRC17 in sEVs

1 Experiment ID 497 MISEV standards ✘ Biophysical techniques ✔ CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35931686     Organism Homo sapiens Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD." Journal name Cell Death Dis Publication year 2022 Sample Chondrocytes Sample name T/C-28a2 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

2 Experiment ID 498 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35931686     Organism Homo sapiens Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD." Journal name Cell Death Dis Publication year 2022 Sample Chondrocytes Sample name T/C-28a2 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

3 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

Protein-protein interactions for LRRC17

Protein Interactor ExoCarta ID Identification method PubMed Species 1 CNPY4 245812 Affinity Capture-MS Homo sapiens 2 C1QBP 708 Affinity Capture-MS Homo sapiens 3 LRBA 987 Affinity Capture-MS Homo sapiens 4 PRKCI 5584 Affinity Capture-MS Homo sapiens 5 HECTD3 79654 Affinity Capture-MS Homo sapiens 6 PRTN3 5657 Affinity Capture-MS Homo sapiens 7 ZZEF1 23140 Affinity Capture-MS Homo sapiens 8 CTSG 1511 Affinity Capture-MS Homo sapiens 9 MPO 4353 Affinity Capture-MS Homo sapiens 10 LTF 4057 Affinity Capture-MS Homo sapiens 11 ARMCX3 51566 Affinity Capture-MS Homo sapiens 12 TMEM160 54958 Affinity Capture-MS Homo sapiens 13 BCL7B   Affinity Capture-MS Homo sapiens 14 RANBP6 26953 Affinity Capture-MS Homo sapiens 15 CNPY3 10695 Affinity Capture-MS Homo sapiens 16 TEFM   Affinity Capture-MS Homo sapiens 17 TMEM214 54867 Affinity Capture-MS Homo sapiens 18 KBTBD7   Affinity Capture-MS Homo sapiens 19 FGG 2266 Affinity Capture-MS Homo sapiens 20 SOX2   Affinity Capture-MS Homo sapiens View the network

Pathways in which LRRC17 is involved

No pathways found