Gene description for CELF2
Gene name CUGBP, Elav-like family member 2
Gene symbol CELF2
Other names/aliases BRUNOL3
CUGBP2
ETR-3
ETR3
NAPOR
Species Homo sapiens
 Database cross references - CELF2
ExoCarta ExoCarta_10659
Vesiclepedia VP_10659
Entrez Gene 10659
HGNC 2550
MIM 602538
UniProt O95319  
 CELF2 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CELF2
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA 3'-UTR binding GO:0003730 IBA
    pre-mRNA binding GO:0036002 IDA
Biological Process
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 IBA
    mRNA splice site recognition GO:0006376 IBA
    mRNA splice site recognition GO:0006376 IDA
    RNA processing GO:0006396 TAS
    regulation of heart contraction GO:0008016 TAS
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 IMP
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IBA
    intracellular membrane-bounded organelle GO:0043231 IDA
    Flemming body GO:0090543 IDA
    ribonucleoprotein complex GO:1990904 IBA
 Experiment description of studies that identified CELF2 in sEVs
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CELF2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
2 FN1 2335
Affinity Capture-MS Homo sapiens
3 PDK1 5163
Affinity Capture-MS Homo sapiens
4 Nedd1  
Affinity Capture-MS Mus musculus
5 HSD3B7 80270
Proximity Label-MS Homo sapiens
6 PCBP1 5093
Two-hybrid Homo sapiens
7 PTGS2 5743
Protein-RNA Homo sapiens
8 TCEB2 6923
Affinity Capture-MS Homo sapiens
9 ELAVL1 1994
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
10 CEBPA  
Protein-peptide Homo sapiens
11 HNRNPA1 3178
Proximity Label-MS Homo sapiens
12 A1CF  
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
13 Csk 12988
Affinity Capture-MS Mus musculus
14 Apob 54225
Affinity Capture-RNA Rattus norvegicus
View the network image/svg+xml
 Pathways in which CELF2 is involved
No pathways found





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