Gene description for Acta2
Gene name	actin, alpha 2, smooth muscle, aorta
Gene symbol	Acta2
Other names/aliases	0610041G09Rik Actvs SMalphaA a-SMA alphaSMA
Species	Mus musculus
Database cross references - Acta2
ExoCarta	ExoCarta_11475
Vesiclepedia	VP_11475
Entrez Gene	11475
UniProt	P62737
Acta2 identified in sEVs derived from the following tissue/cell type
Fibroblasts	23260141
Oligodendrocytes	21136642
Pancreatic cells	19351151

Gene ontology annotations for Acta2

Molecular Function     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     hydrolase activity GO:0016787 IEA     protein kinase binding GO:0019901 IPI Biological Process     muscle contraction GO:0006936 ISO     regulation of blood pressure GO:0008217 IMP     response to virus GO:0009615 IEA     positive regulation of gene expression GO:0010628 ISS     vascular associated smooth muscle contraction GO:0014829 IMP     positive regulation of hepatic stellate cell migration GO:0061870 IEA     positive regulation of hepatic stellate cell migration GO:0061870 ISO     positive regulation of hepatic stellate cell contraction GO:0061874 IEA     positive regulation of hepatic stellate cell contraction GO:0061874 ISO     positive regulation of ERK1 and ERK2 cascade GO:0070374 IEA     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     cellular response to transforming growth factor beta stimulus GO:0071560 IEA     juxtaglomerular apparatus development GO:0072051 IEA     glomerular mesangial cell development GO:0072144 IEA     mesenchyme migration GO:0090131 ISS     positive regulation of hepatic stellate cell activation GO:2000491 IEA     positive regulation of hepatic stellate cell activation GO:2000491 ISO Subcellular Localization     stress fiber GO:0001725 IEA     stress fiber GO:0001725 ISO     basement membrane GO:0005604 IEA     basement membrane GO:0005604 ISO     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 ISO     cytoskeleton GO:0005856 IDA     actin cytoskeleton GO:0015629 IBA     actin cytoskeleton GO:0015629 IDA     actin cytoskeleton GO:0015629 ISO     lamellipodium GO:0030027 ISS     filopodium GO:0030175 ISS     smooth muscle contractile fiber GO:0030485 IDA     motile cilium GO:0031514 IDA     protein-containing complex GO:0032991 IEA     cell body GO:0044297 ISS