Gene description for Hyou1
Gene name
hypoxia up-regulated 1
Gene symbol
Hyou1
Other names/aliases
AI415631 CBP-140 Cab140 Grp170 Orp150
Species
Mus musculus
Database cross references - Hyou1
ExoCarta
ExoCarta_12282
Vesiclepedia
VP_12282
Entrez Gene
12282
UniProt
Q9JKR6
Hyou1 identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
Fibroblasts
23260141
T-cell lymphoma cells
37309723
Gene ontology annotations for Hyou1
Experiment description of studies that identified Hyou1 in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
210
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|FLOT1
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23260141
Organism
Mus musculus
Experiment description
Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors
"Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name
Cell
Publication year
2012
Sample
Fibroblasts
Sample name
Normal-Fibroblasts (L cells)
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Hyou1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Kctd13
Affinity Capture-MS
Mus musculus
2
Sec61a1
Affinity Capture-Western
Mus musculus
Co-fractionation
Mus musculus
Affinity Capture-Western
Mus musculus
3
Sil1
Dosage Rescue
Mus musculus
Synthetic Haploinsufficiency
Mus musculus
4
Stub1
56424
Affinity Capture-Western
Mus musculus
Affinity Capture-Western
Mus musculus
5
Lmo2
Two-hybrid
Mus musculus
6
Tmed10
68581
Co-fractionation
Mus musculus
7
Eed
Affinity Capture-MS
Mus musculus
8
Hspa5
14828
Affinity Capture-Western
Mus musculus
Affinity Capture-Western
Mus musculus
9
Atxn1
Affinity Capture-MS
Mus musculus
10
Vcp
269523
Affinity Capture-Western
Mus musculus
Affinity Capture-Western
Mus musculus
11
Os9
Co-fractionation
Mus musculus
12
Fancd2
Affinity Capture-MS
Mus musculus
View the network
image/svg+xml
Pathways in which Hyou1 is involved
No pathways found