Gene description for Dnm1
Gene name	dynamin 1
Gene symbol	Dnm1
Other names/aliases	Dnm
Species	Rattus norvegicus
Database cross references - Dnm1
ExoCarta	ExoCarta_140694
Vesiclepedia	VP_140694
Entrez Gene	140694
UniProt	P21575
Dnm1 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells	20124479
Pancreatic cancer cells	20124479

Gene ontology annotations for Dnm1

Molecular Function     GTPase activity GO:0003924 IBA     GTPase activity GO:0003924 IEA     GTPase activity GO:0003924 ISO     GTPase activity GO:0003924 ISS     GTPase activity GO:0003924 TAS     protein binding GO:0005515 IPI     GTP binding GO:0005525 IEA     phosphatidylinositol-4,5-bisphosphate binding GO:0005546 IEA     phosphatidylinositol-4,5-bisphosphate binding GO:0005546 ISO     phosphatidylinositol-4,5-bisphosphate binding GO:0005546 ISS     phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 IEA     phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 ISO     microtubule binding GO:0008017 IBA     SH3 domain binding GO:0017124 IDA     SH3 domain binding GO:0017124 IPI     GDP binding GO:0019003 IEA     GDP binding GO:0019003 ISO     GDP binding GO:0019003 ISS     protein kinase binding GO:0019901 IEA     protein kinase binding GO:0019901 ISO     D2 dopamine receptor binding GO:0031749 IPI     identical protein binding GO:0042802 IPI     identical protein binding GO:0042802 ISO     identical protein binding GO:0042802 TAS     protein homodimerization activity GO:0042803 IEA     protein homodimerization activity GO:0042803 ISO     protein homodimerization activity GO:0042803 ISS     protein-containing complex binding GO:0044877 IDA     protein-containing complex binding GO:0044877 IPI     nitric-oxide synthase binding GO:0050998 IPI     protein serine/threonine kinase binding GO:0120283 IPI     membrane scission GTPase motor activity GO:1990606 IEA Biological Process     G protein-coupled receptor internalization GO:0002031 IMP     endocytosis GO:0006897 IEA     endocytosis GO:0006897 ISO     receptor-mediated endocytosis GO:0006898 IMP     receptor-mediated endocytosis GO:0006898 ISO     receptor-mediated endocytosis GO:0006898 ISS     endosome organization GO:0007032 IEA     endosome organization GO:0007032 ISO     synaptic vesicle budding from presynaptic endocytic zone membrane GO:0016185 IBA     receptor internalization GO:0031623 IBA     receptor internalization GO:0031623 IMP     synaptic vesicle endocytosis GO:0048488 IEA     synaptic vesicle endocytosis GO:0048488 ISO     modulation of chemical synaptic transmission GO:0050804 IEA     modulation of chemical synaptic transmission GO:0050804 ISO     protein homooligomerization GO:0051260 ISO     protein homotetramerization GO:0051289 IEA     protein homotetramerization GO:0051289 ISO     protein homotetramerization GO:0051289 ISS     regulation of vesicle size GO:0097494 IEA     regulation of vesicle size GO:0097494 ISO     regulation of vesicle size GO:0097494 ISS     clathrin coat assembly involved in endocytosis GO:0099049 IEA     clathrin coat assembly involved in endocytosis GO:0099049 ISO     clathrin coat assembly involved in endocytosis GO:0099049 ISS     vesicle scission GO:0099050 IEA     vesicle scission GO:0099050 ISO     vesicle scission GO:0099050 ISS     regulation of synaptic vesicle endocytosis GO:1900242 IMP     positive regulation of synaptic vesicle endocytosis GO:1900244 IMP     positive regulation of synaptic vesicle recycling GO:1903423 IMP     response to amyloid-beta GO:1904645 IEP Subcellular Localization     photoreceptor inner segment GO:0001917 IEA     photoreceptor inner segment GO:0001917 ISO     cytoplasm GO:0005737 IBA     Golgi apparatus GO:0005794 IDA     Golgi apparatus GO:0005794 IEA     microtubule GO:0005874 IBA     microtubule GO:0005874 IEA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 TAS     clathrin-coated pit GO:0005905 IEA     clathrin-coated pit GO:0005905 ISO     clathrin-coated pit GO:0005905 ISS     synaptic vesicle GO:0008021 IDA     membrane coat GO:0030117 IEA     membrane coat GO:0030117 ISO     clathrin-coated vesicle GO:0030136 IDA     clathrin-coated vesicle GO:0030136 IEA     endocytic vesicle GO:0030139 IDA     protein-containing complex GO:0032991 IDA     chromaffin granule GO:0042583 IEA     neuron projection GO:0043005 IEA     varicosity GO:0043196 IDA     synapse GO:0045202 IBA     photoreceptor ribbon synapse GO:0098684 IEA     photoreceptor ribbon synapse GO:0098684 ISO     presynapse GO:0098793 IDA     presynaptic endocytic zone membrane GO:0098835 IDA     presynaptic endocytic zone membrane GO:0098835 IEA     presynaptic endocytic zone membrane GO:0098835 ISO     glutamatergic synapse GO:0098978 IEA     glutamatergic synapse GO:0098978 ISO