Gene description for CSF2
Gene name	colony stimulating factor 2 (granulocyte-macrophage)
Gene symbol	CSF2
Other names/aliases	GMCSF
Species	Homo sapiens
Database cross references - CSF2
ExoCarta	ExoCarta_1437
Vesiclepedia	VP_1437
Entrez Gene	1437
HGNC	2434
MIM	138960
UniProt	P04141
CSF2 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for CSF2

Molecular Function     cytokine activity GO:0005125 IBA     cytokine activity GO:0005125 IDA     granulocyte macrophage colony-stimulating factor receptor binding GO:0005129 IEA     protein binding GO:0005515 IPI     growth factor activity GO:0008083 IEA Biological Process     histamine secretion GO:0001821 IEA     embryonic placenta development GO:0001892 IEA     immune response GO:0006955 IEA     cell surface receptor signaling pathway via JAK-STAT GO:0007259 IDA     cell population proliferation GO:0008283 IEA     positive regulation of cell population proliferation GO:0008284 IDA     positive regulation of gene expression GO:0010628 IDA     positive regulation of macrophage derived foam cell differentiation GO:0010744 IDA     myeloid cell differentiation GO:0030099 IBA     neutrophil differentiation GO:0030223 IEA     monocyte differentiation GO:0030224 IEA     macrophage differentiation GO:0030225 IDA     positive regulation of cell migration GO:0030335 IEA     positive regulation of interleukin-23 production GO:0032747 IDA     response to silicon dioxide GO:0034021 IEA     response to fluid shear stress GO:0034405 IEA     granulocyte-macrophage colony-stimulating factor signaling pathway GO:0038157 IDA     epithelial fluid transport GO:0042045 IEA     myeloid dendritic cell differentiation GO:0043011 IDA     regulation of circadian sleep/wake cycle, sleep GO:0045187 IEA     negative regulation of DNA-templated transcription GO:0045892 IDA     positive regulation of leukocyte proliferation GO:0070665 IDA     cellular response to lipopolysaccharide GO:0071222 IEA     positive regulation of podosome assembly GO:0071803 IDA     cellular response to granulocyte macrophage colony-stimulating factor stimulus GO:0097011 IDA     dendritic cell differentiation GO:0097028 IDA     cell surface receptor signaling pathway via STAT GO:0097696 IDA     negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 IDA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IDA     plasma membrane GO:0005886 NAS     granulocyte macrophage colony-stimulating factor receptor complex GO:0030526 IDA     intracellular membrane-bounded organelle GO:0043231 IDA