Gene description for Itsn1
Gene name	intersectin 1 (SH3 domain protein 1A)
Gene symbol	Itsn1
Other names/aliases	AA517634 AA545208 AI316805 AI839402 AI848451 Ehsh1 Ese1 Itsn Sh3p17
Species	Mus musculus
Database cross references - Itsn1
ExoCarta	ExoCarta_16443
Vesiclepedia	VP_16443
Entrez Gene	16443
UniProt	Q9Z0R4
Itsn1 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Itsn1

Molecular Function     guanyl-nucleotide exchange factor activity GO:0005085 IEA     calcium ion binding GO:0005509 IEA     protein binding GO:0005515 IPI     kinase activator activity GO:0019209 IDA     molecular adaptor activity GO:0060090 IBA     molecular adaptor activity GO:0060090 ISO     proline-rich region binding GO:0070064 ISO Biological Process     exocytosis GO:0006887 IEA     endocytosis GO:0006897 IMP     small GTPase-mediated signal transduction GO:0007264 IDA     cell-cell signaling GO:0007267 IMP     protein localization GO:0008104 ISO     protein transport GO:0015031 IEA     endosomal transport GO:0016197 IBA     negative regulation of neuron apoptotic process GO:0043524 IMP     synaptic vesicle endocytosis GO:0048488 IDA     synaptic vesicle endocytosis GO:0048488 IMP     neuron apoptotic process GO:0051402 IMP     positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 IDA     positive regulation of growth hormone secretion GO:0060124 ISO     positive regulation of dendritic spine development GO:0060999 ISO     regulation of postsynapse organization GO:0099175 ISO     clathrin-dependent synaptic vesicle endocytosis GO:0150007 IBA     regulation of modification of postsynaptic actin cytoskeleton GO:1905274 ISO     positive regulation of caveolin-mediated endocytosis GO:2001288 ISO Subcellular Localization     nuclear envelope GO:0005635 IEA     nuclear envelope GO:0005635 ISO     nuclear envelope GO:0005635 ISS     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISS     cytosol GO:0005829 IDA     cytosol GO:0005829 TAS     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     clathrin-coated pit GO:0005905 IDA     clathrin-coated pit GO:0005905 ISO     clathrin-coated pit GO:0005905 ISO     lamellipodium GO:0030027 IDA     endocytic vesicle GO:0030139 IDA     presynaptic membrane GO:0042734 IBA     neuronal cell body GO:0043025 ISO     dendritic spine GO:0043197 ISO     calyx of Held GO:0044305 IDA     recycling endosome GO:0055037 IEA     apical dendrite GO:0097440 ISO     intracellular vesicle GO:0097708 IBA     intracellular vesicle GO:0097708 ISO     presynaptic endocytic zone GO:0098833 IDA     postsynaptic actin cytoskeleton GO:0098871 ISO     glutamatergic synapse GO:0098978 ISO