Gene description for Rps6ka2
Gene name	ribosomal protein S6 kinase, polypeptide 2
Gene symbol	Rps6ka2
Other names/aliases	90kDa D17Wsu134e Rps6ka-rs1 Rsk3 p90rsk pp90rsk
Species	Mus musculus
Database cross references - Rps6ka2
ExoCarta	ExoCarta_20112
Vesiclepedia	VP_20112
Entrez Gene	20112
UniProt	Q9WUT3
Rps6ka2 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Rps6ka2

Molecular Function     magnesium ion binding GO:0000287 IEA     protein kinase activity GO:0004672 IDA     protein serine/threonine kinase activity GO:0004674 IDA     protein serine/threonine kinase activity GO:0004674 TAS     3-phosphoinositide-dependent protein kinase activity GO:0004676 IEA     DNA-dependent protein kinase activity GO:0004677 IEA     AMP-activated protein kinase activity GO:0004679 IEA     eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 IEA     ribosomal protein S6 kinase activity GO:0004711 IBA     ribosomal protein S6 kinase activity GO:0004711 IDA     protein serine/threonine/tyrosine kinase activity GO:0004712 ISO     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     histone H3S10 kinase activity GO:0035175 IEA     histone H3T11 kinase activity GO:0035402 IEA     histone H3T6 kinase activity GO:0035403 IEA     histone H2AXS139 kinase activity GO:0035979 IEA     histone H3S28 kinase activity GO:0044022 IEA     histone H4S1 kinase activity GO:0044023 IEA     histone H2AS1 kinase activity GO:0044024 IEA     histone H2BS14 kinase activity GO:0044025 IEA     histone H3T3 kinase activity GO:0072354 IEA     histone H2AS121 kinase activity GO:0072371 IEA     Rho-dependent protein serine/threonine kinase activity GO:0072518 IEA     protein serine kinase activity GO:0106310 IEA     histone H2BS36 kinase activity GO:0140823 IEA     histone H3S57 kinase activity GO:0140855 IEA     histone H3T45 kinase activity GO:0140857 IEA     histone H2AT120 kinase activity GO:1990244 IEA Biological Process     oocyte maturation GO:0001556 IDA     brain renin-angiotensin system GO:0002035 IDA     chromatin remodeling GO:0006338 IEA     protein phosphorylation GO:0006468 IDA     heart development GO:0007507 IDA     negative regulation of cell population proliferation GO:0008285 ISO     negative regulation of cell population proliferation GO:0008285 ISS     positive regulation of gene expression GO:0010628 IDA     cardiac muscle cell apoptotic process GO:0010659 IDA     peptidyl-serine phosphorylation GO:0018105 IDA     intracellular signal transduction GO:0035556 IEA     TORC1 signaling GO:0038202 IBA     positive regulation of apoptotic process GO:0043065 ISO     positive regulation of apoptotic process GO:0043065 ISS     negative regulation of cell cycle GO:0045786 ISO     negative regulation of cell cycle GO:0045786 ISS     negative regulation of meiotic nuclear division GO:0045835 IDA     heart contraction GO:0060047 IDA     regulation of protein processing GO:0070613 IMP     cellular response to carbohydrate stimulus GO:0071322 IDA Subcellular Localization     nucleus GO:0005634 ISO     nucleus GO:0005634 ISS     nucleoplasm GO:0005654 IBA     nucleoplasm GO:0005654 ISO     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 ISO     spindle GO:0005819 IDA     meiotic spindle GO:0072687 IDA