Gene description for FCN1
Gene name	ficolin (collagen/fibrinogen domain containing) 1
Gene symbol	FCN1
Other names/aliases	FCNM
Species	Homo sapiens
Database cross references - FCN1
ExoCarta	ExoCarta_2219
Vesiclepedia	VP_2219
Entrez Gene	2219
HGNC	3623
MIM	601252
UniProt	O00602
FCN1 identified in sEVs derived from the following tissue/cell type
Plasma	19028452

Gene ontology annotations for FCN1

Molecular Function     G protein-coupled receptor binding GO:0001664 IPI     antigen binding GO:0003823 IBA     signaling receptor binding GO:0005102 IBA     protein binding GO:0005515 IPI     carbohydrate binding GO:0030246 IEA     sialic acid binding GO:0033691 IDA     pattern recognition receptor activity GO:0038187 IMP     metal ion binding GO:0046872 IEA     carbohydrate derivative binding GO:0097367 IBA Biological Process     complement activation, lectin pathway GO:0001867 IBA     complement activation, lectin pathway GO:0001867 IDA     cell surface pattern recognition receptor signaling pathway GO:0002752 IMP     cell surface pattern recognition receptor signaling pathway GO:0002752 NAS     proteolysis GO:0006508 IDA     G protein-coupled receptor signaling pathway GO:0007186 IDA     positive regulation of interleukin-8 production GO:0032757 IMP     protein localization to cell surface GO:0034394 IDA     recognition of apoptotic cell GO:0043654 IDA     negative regulation of viral entry into host cell GO:0046597 IDA     positive regulation of opsonization GO:1903028 IDA Subcellular Localization     extracellular region GO:0005576 TAS     collagen trimer GO:0005581 IEA     extracellular space GO:0005615 IBA     extracellular space GO:0005615 NAS     plasma membrane GO:0005886 IDA     external side of plasma membrane GO:0009897 NAS     secretory granule lumen GO:0034774 TAS     collagen-containing extracellular matrix GO:0062023 HDA     collagen-containing extracellular matrix GO:0062023 IBA     ficolin-1-rich granule lumen GO:1904813 TAS     serine-type endopeptidase complex GO:1905370 IDA