Experiment description of studies that identified HIC2 in sEVs

1 Experiment ID 274 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81 Enriched markers ✔ AIF Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25844599     Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T." Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 - Docetaxel resistant Isolation/purification methods Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Flow cytometry Western blotting

Protein-protein interactions for HIC2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 E4F1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 PRICKLE3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 LIG4 3981 Affinity Capture-MS Homo sapiens 4 YY1AP1 55249 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 MECP2 4204 Affinity Capture-MS Homo sapiens 6 KLF8   Affinity Capture-MS Homo sapiens 7 FASN 2194 Positive Genetic Homo sapiens 8 FOXA3   Affinity Capture-MS Homo sapiens 9 TMED9 54732 Affinity Capture-MS Homo sapiens 10 FEV   Proximity Label-MS Homo sapiens 11 HORMAD2   Affinity Capture-MS Homo sapiens 12 TBCCD1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 MCF2L2 23101 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 CTBP2 1488 Affinity Capture-MS Homo sapiens 15 ZBTB8A   Two-hybrid Homo sapiens 16 FOXJ2   Affinity Capture-MS Homo sapiens 17 CALU 813 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 FOXB1   Affinity Capture-MS Homo sapiens 19 UFL1 23376 Affinity Capture-MS Homo sapiens 20 ZNF169 169841 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 21 CUL3 8452 Affinity Capture-MS Homo sapiens 22 VWA5A 4013 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 ZNF460   Affinity Capture-MS Homo sapiens 24 HIC1   Two-hybrid Homo sapiens Co-localization Homo sapiens 25 APP 351 Reconstituted Complex Homo sapiens 26 APEX1 328 Affinity Capture-RNA Homo sapiens 27 MIF 4282 Affinity Capture-MS Homo sapiens 28 LZTS2 84445 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 29 C12orf49   Positive Genetic Homo sapiens 30 HIC2 23119 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 31 CEP70   Two-hybrid Homo sapiens 32 BARD1 580 Affinity Capture-MS Homo sapiens 33 CTBP1 1487 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 34 EHMT2 10919 Two-hybrid Homo sapiens 35 PNMA2   Affinity Capture-MS Homo sapiens 36 BRD1 23774 Affinity Capture-MS Homo sapiens 37 S100B 6285 Affinity Capture-MS Homo sapiens 38 DDRGK1 65992 Affinity Capture-MS Homo sapiens 39 FOXQ1   Affinity Capture-MS Homo sapiens 40 BRPF3   Affinity Capture-MS Homo sapiens 41 KLF15   Proximity Label-MS Homo sapiens 42 EP300 2033 Affinity Capture-MS Homo sapiens 43 TEX19   Affinity Capture-MS Homo sapiens 44 FBLN5 10516 Affinity Capture-MS Homo sapiens View the network

Pathways in which HIC2 is involved

No pathways found