Gene description for Farsb
Gene name phenylalanyl-tRNA synthetase, beta subunit
Gene symbol Farsb
Other names/aliases C76708
Farsa
Farsl
Farslb
Frsb
Species Mus musculus
 Database cross references - Farsb
ExoCarta ExoCarta_23874
Vesiclepedia VP_23874
Entrez Gene 23874
UniProt Q9WUA2  
 Farsb identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Farsb
Molecular Function
    magnesium ion binding GO:0000287 ISS
    RNA binding GO:0003723 IEA
    phenylalanine-tRNA ligase activity GO:0004826 IBA
    phenylalanine-tRNA ligase activity GO:0004826 ISO
    phenylalanine-tRNA ligase activity GO:0004826 ISS
    ATP binding GO:0005524 IEA
Biological Process
    phenylalanyl-tRNA aminoacylation GO:0006432 IBA
    phenylalanyl-tRNA aminoacylation GO:0006432 ISO
    phenylalanyl-tRNA aminoacylation GO:0006432 ISS
    protein heterotetramerization GO:0051290 ISO
    protein heterotetramerization GO:0051290 ISS
Subcellular Localization
    phenylalanine-tRNA ligase complex GO:0009328 IBA
    phenylalanine-tRNA ligase complex GO:0009328 ISO
    phenylalanine-tRNA ligase complex GO:0009328 ISS
 Experiment description of studies that identified Farsb in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Farsb
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kctd13  
Affinity Capture-MS Mus musculus
2 Fxr1 14359
Affinity Capture-MS Mus musculus
3 Set 56086
Co-fractionation Mus musculus
4 Atxn1  
Affinity Capture-MS Mus musculus
5 Eed  
Affinity Capture-MS Mus musculus
6 Atg16l1  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Farsb is involved
No pathways found





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