Gene description for MAP7D2
Gene name MAP7 domain containing 2
Gene symbol MAP7D2
Other names/aliases -
Species Homo sapiens
 Database cross references - MAP7D2
ExoCarta ExoCarta_256714
Vesiclepedia VP_256714
Entrez Gene 256714
HGNC 25899
UniProt Q96T17  
 MAP7D2 identified in sEVs derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for MAP7D2
Biological Process
    microtubule cytoskeleton organization GO:0000226 IBA
Subcellular Localization
    microtubule cytoskeleton GO:0015630 IBA
 Experiment description of studies that identified MAP7D2 in sEVs
1
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for MAP7D2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZRANB1 54764
Affinity Capture-MS Homo sapiens
2 EIF3A 8661
Cross-Linking-MS (XL-MS) Homo sapiens
3 NEURL4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 KLHL20  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 IL17RA 23765
Affinity Capture-MS Homo sapiens
6 KIF2A 3796
Proximity Label-MS Homo sapiens
7 HIST1H2BO 8348
Cross-Linking-MS (XL-MS) Homo sapiens
8 SIRT6  
Affinity Capture-MS Homo sapiens
9 CLIP1 6249
Proximity Label-MS Homo sapiens
10 CLINT1 9685
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 MAGEA3  
Affinity Capture-MS Homo sapiens
12 UBE3A 7337
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 CENPF 1063
Affinity Capture-MS Homo sapiens
14 INSIG2  
Affinity Capture-MS Homo sapiens
15 SH3GL1 6455
Affinity Capture-MS Homo sapiens
16 TRIM52  
Affinity Capture-MS Homo sapiens
17 RPA2 6118
Proximity Label-MS Homo sapiens
18 P4HA2 8974
Affinity Capture-MS Homo sapiens
19 TRIM27  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 MEX3A  
Affinity Capture-RNA Homo sapiens
21 HSPA12B 116835
Proximity Label-MS Homo sapiens
22 KIF20A 10112
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 EFNB1 1947
Affinity Capture-MS Homo sapiens
24 FHL3 2275
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 CDH23 64072
Affinity Capture-MS Homo sapiens
26 ARHGAP18 93663
Affinity Capture-MS Homo sapiens
27 CAMSAP2  
Proximity Label-MS Homo sapiens
28 OLFML3 56944
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 EIF2B5 8893
Affinity Capture-MS Homo sapiens
30 MAPRE1 22919
Proximity Label-MS Homo sapiens
31 ECI2 10455
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 MAPRE3  
Proximity Label-MS Homo sapiens
33 LONP2 83752
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
35 USP20  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 RPA3 6119
Proximity Label-MS Homo sapiens
37 CLTA 1211
Affinity Capture-MS Homo sapiens
38 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
39 HERC2 8924
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 KIF5B 3799
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 PNMA2  
Affinity Capture-MS Homo sapiens
42 DCTN1 1639
Proximity Label-MS Homo sapiens
43 NDC80 10403
Proximity Label-MS Homo sapiens
44 BICD2 23299
Proximity Label-MS Homo sapiens
45 STX8 9482
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 BEND3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
48 PIK3C2A 5286
Affinity Capture-MS Homo sapiens
49 EFNB2 1948
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 TOMM20 9804
Cross-Linking-MS (XL-MS) Homo sapiens
51 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml
 Pathways in which MAP7D2 is involved
No pathways found





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