Experiment description of studies that identified BACE2 in sEVs

1 Experiment ID 200 MISEV standards ✔ EM Biophysical techniques ✔ HSP70|HSP90|TSG101|Alix|GAPDH Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 22635005     Organism Homo sapiens Experiment description Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Authors "Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D." Journal name Nat Med Publication year 2012 Sample Melanoma cells Sample name B16-F10 SK-MEL-202 SK-MEL035 SK-MEL-265 Isolation/purification methods Differential centrifugation Filtration Sucrose cushion Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for BACE2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 TUBA3C 7278 Affinity Capture-MS Homo sapiens 2 ZDHHC20 253832 Affinity Capture-MS Homo sapiens 3 UPK2 7379 Affinity Capture-MS Homo sapiens 4 DEPDC1   Affinity Capture-MS Homo sapiens 5 CHAMP1   Affinity Capture-MS Homo sapiens 6 DEPDC1B 55789 Affinity Capture-MS Homo sapiens 7 CENPN   Affinity Capture-MS Homo sapiens 8 BCR 613 Affinity Capture-MS Homo sapiens 9 OCLN 100506658 Affinity Capture-MS Homo sapiens 10 TMEM106A   Affinity Capture-MS Homo sapiens 11 C4orf32   Affinity Capture-MS Homo sapiens 12 TMEM30A 55754 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 PAPOLA 10914 Affinity Capture-MS Homo sapiens 14 FAM20C 56975 Affinity Capture-MS Homo sapiens 15 TTC5   Affinity Capture-MS Homo sapiens 16 XPR1 9213 Affinity Capture-MS Homo sapiens 17 KIDINS220 57498 Affinity Capture-MS Homo sapiens 18 HLA-E 3133 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 TMPRSS11B 132724 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 CLEC2B   Affinity Capture-MS Homo sapiens 21 ZDHHC12   Affinity Capture-MS Homo sapiens 22 HPN   Affinity Capture-MS Homo sapiens 23 POGZ 23126 Affinity Capture-MS Homo sapiens 24 USP36   Affinity Capture-MS Homo sapiens 25 CLEC2D   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 ABL1 25 Affinity Capture-MS Homo sapiens 27 FAM171A1 221061 Affinity Capture-MS Homo sapiens 28 PRG2   Affinity Capture-MS Homo sapiens 29 CDC23 8697 Affinity Capture-MS Homo sapiens 30 CTPS2 56474 Affinity Capture-MS Homo sapiens 31 CHST6   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 IFNE   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 PUM2 23369 Affinity Capture-MS Homo sapiens 34 ZC3H4 23211 Affinity Capture-MS Homo sapiens 35 ATP1B3 483 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 36 CLSTN1 22883 Affinity Capture-MS Homo sapiens 37 PAPOLG   Affinity Capture-MS Homo sapiens 38 PRRC2B   Affinity Capture-MS Homo sapiens 39 FADS1 3992 Affinity Capture-MS Homo sapiens 40 NDFIP1 80762 Affinity Capture-MS Homo sapiens 41 WDR36 134430 Affinity Capture-MS Homo sapiens 42 RP9   Affinity Capture-MS Homo sapiens 43 ABCD1 215 Affinity Capture-MS Homo sapiens 44 FAM126A 84668 Affinity Capture-MS Homo sapiens 45 TUBA4A 7277 Affinity Capture-MS Homo sapiens 46 SOAT1 6646 Affinity Capture-MS Homo sapiens 47 CTAGE5 4253 Affinity Capture-MS Homo sapiens 48 L3MBTL3   Affinity Capture-MS Homo sapiens 49 TUBA1C 84790 Affinity Capture-MS Homo sapiens 50 ARSG 22901 Affinity Capture-MS Homo sapiens 51 PCDHGA9   Affinity Capture-MS Homo sapiens 52 FAM171A2 284069 Affinity Capture-MS Homo sapiens 53 CD1E   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 54 LEMD2 221496 Affinity Capture-MS Homo sapiens 55 Kif13b   Affinity Capture-MS Mus musculus 56 NAV1 89796 Affinity Capture-MS Homo sapiens 57 TCTN2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 58 MIA3 375056 Affinity Capture-MS Homo sapiens 59 PPP1R10   Affinity Capture-MS Homo sapiens 60 HLA-DRB3 3125 Affinity Capture-MS Homo sapiens 61 GGA2 23062 Protein-peptide Homo sapiens Reconstituted Complex Homo sapiens 62 TUBA1B 10376 Affinity Capture-MS Homo sapiens 63 MPPE1 65258 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 64 KLRC1   Affinity Capture-MS Homo sapiens 65 BAGE2   Affinity Capture-MS Homo sapiens 66 ST14 6768 Affinity Capture-MS Homo sapiens 67 PIK3C2A 5286 Affinity Capture-MS Homo sapiens 68 PKP4 8502 Affinity Capture-MS Homo sapiens 69 MVK 4598 Affinity Capture-MS Homo sapiens 70 RUFY3   Affinity Capture-MS Homo sapiens 71 GGA1 26088 Protein-peptide Homo sapiens Reconstituted Complex Homo sapiens 72 ADGRE5 976 Affinity Capture-MS Homo sapiens 73 DDX51   Affinity Capture-MS Homo sapiens 74 TENM3 55714 Affinity Capture-MS Homo sapiens 75 ST8SIA4 7903 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens View the network

Pathways in which BACE2 is involved

No pathways found