Gene description for LIFR
Gene name	leukemia inhibitory factor receptor alpha
Gene symbol	LIFR
Other names/aliases	CD118 LIF-R SJS2 STWS SWS
Species	Homo sapiens
Database cross references - LIFR
ExoCarta	ExoCarta_3977
Vesiclepedia	VP_3977
Entrez Gene	3977
HGNC	6597
MIM	151443
UniProt	P42702
LIFR identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for LIFR

Molecular Function     cytokine receptor activity GO:0004896 IBA     ciliary neurotrophic factor receptor activity GO:0004897 IDA     leukemia inhibitory factor receptor activity GO:0004923 IDA     leukemia inhibitory factor receptor activity GO:0004923 IDA     oncostatin-M receptor activity GO:0004924 IBA     oncostatin-M receptor activity GO:0004924 IDA     ciliary neurotrophic factor receptor binding GO:0005127 IBA     ciliary neurotrophic factor receptor binding GO:0005127 IPI     protein binding GO:0005515 IPI     growth factor binding GO:0019838 IPI     cytokine binding GO:0019955 IBA Biological Process     cell surface receptor signaling pathway GO:0007166 TAS     positive regulation of cell population proliferation GO:0008284 IBA     positive regulation of cell population proliferation GO:0008284 IDA     positive regulation of cell population proliferation GO:0008284 IDA     cytokine-mediated signaling pathway GO:0019221 IBA     cytokine-mediated signaling pathway GO:0019221 IDA     response to cytokine GO:0034097 IDA     oncostatin-M-mediated signaling pathway GO:0038165 IMP     leukemia inhibitory factor signaling pathway GO:0048861 IDA     ciliary neurotrophic factor-mediated signaling pathway GO:0070120 IDA Subcellular Localization     plasma membrane GO:0005886 TAS     external side of plasma membrane GO:0009897 IBA     receptor complex GO:0043235 IBA     receptor complex GO:0043235 IDA     extracellular exosome GO:0070062 HDA