Gene description for P2RX5
Gene name	purinergic receptor P2X, ligand gated ion channel, 5
Gene symbol	P2RX5
Other names/aliases	LRH-1 P2X5 P2X5R
Species	Homo sapiens
Database cross references - P2RX5
ExoCarta	ExoCarta_5026
Vesiclepedia	VP_5026
Entrez Gene	5026
HGNC	8536
MIM	602836
UniProt	Q93086
P2RX5 identified in sEVs derived from the following tissue/cell type
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513

Gene ontology annotations for P2RX5

Molecular Function     purinergic nucleotide receptor activity GO:0001614 NAS     transmembrane signaling receptor activity GO:0004888 TAS     extracellularly ATP-gated monoatomic cation channel activity GO:0004931 IBA     extracellularly ATP-gated monoatomic cation channel activity GO:0004931 NAS     monoatomic ion channel activity GO:0005216 TAS     voltage-gated monoatomic ion channel activity GO:0005244 IEA     ATP binding GO:0005524 NAS     ATP-gated ion channel activity GO:0035381 IDA     identical protein binding GO:0042802 IEA     ligand-gated monoatomic anion channel activity GO:0099095 IDA Biological Process     chloride transport GO:0006821 IDA     signal transduction GO:0007165 TAS     nervous system development GO:0007399 TAS     response to pH GO:0009268 IEA     response to zinc ion GO:0010043 IEA     positive regulation of calcium ion transport into cytosol GO:0010524 NAS     response to ATP GO:0033198 IEA     purinergic nucleotide receptor signaling pathway GO:0035590 IEA     osteoclast maturation GO:0036179 ISS     regulation of skeletal muscle tissue regeneration GO:0043416 IEA     positive regulation of calcium-mediated signaling GO:0050850 NAS     response to calcium ion GO:0051592 IEA     excitatory postsynaptic potential GO:0060079 IEA     calcium ion transmembrane transport GO:0070588 IBA     monoatomic anion transmembrane transport GO:0098656 IEA     positive regulation of calcium ion import across plasma membrane GO:1905665 IEA Subcellular Localization     cytosol GO:0005829 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     postsynapse GO:0098794 IEA