Experiment description of studies that identified CDK17 in sEVs

1 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

2 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for CDK17

Protein Interactor ExoCarta ID Identification method PubMed Species 1 YWHAH 7533 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 APP 351 Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 3 BAG3 9531 Affinity Capture-Luminescence Homo sapiens 4 PCDHA8   Affinity Capture-MS Homo sapiens 5 PPP2R3A   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 Cdk1 12534 Affinity Capture-MS Mus musculus 7 PPP2R5E 5529 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 S100P 6286 Affinity Capture-MS Homo sapiens 9 C12orf43   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 FEM1A   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 SUGP1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 CCNB2   Affinity Capture-MS Homo sapiens 13 PTMA 5757 Affinity Capture-MS Homo sapiens 14 XPO1 7514 Affinity Capture-MS Homo sapiens 15 KCNE3   Affinity Capture-MS Homo sapiens 16 YWHAB 7529 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 17 UNC45A 55898 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 YWHAE 7531 Affinity Capture-MS Homo sapiens 19 CDK16 5127 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 TUBGCP3 10426 Affinity Capture-MS Homo sapiens 21 CDK18 5129 Affinity Capture-MS Homo sapiens 22 YWHAZ 7534 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 UBC 7316 Reconstituted Complex Homo sapiens 24 NOP10 55505 Affinity Capture-MS Homo sapiens 25 TMEM74   Affinity Capture-MS Homo sapiens 26 CDK1 983 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 27 Cdc16   Affinity Capture-MS Mus musculus 28 PRKACA 5566 Affinity Capture-MS Homo sapiens 29 PFDN2 5202 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 30 GAPDH 2597 Affinity Capture-MS Homo sapiens 31 CDK14 5218 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 HDGFRP3 50810 Affinity Capture-MS Homo sapiens 33 DCAF7 10238 Affinity Capture-MS Homo sapiens 34 DHPS 1725 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 35 PNMA2   Affinity Capture-MS Homo sapiens 36 EPHA2 1969 Two-hybrid Homo sapiens 37 SERBP1 26135 Affinity Capture-MS Homo sapiens 38 YWHAQ 10971 Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens 39 S100B 6285 Affinity Capture-MS Homo sapiens 40 KRAS 3845 Proximity Label-MS Homo sapiens 41 YWHAG 7532 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 42 PPP2R5A 5525 Affinity Capture-MS Homo sapiens 43 CDKN1B 1027 Affinity Capture-MS Homo sapiens 44 PPP2R2A 5520 Affinity Capture-MS Homo sapiens 45 TDRD7 23424 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 46 MANSC1 54682 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 47 PPP2CB 5516 Affinity Capture-MS Homo sapiens 48 S100A2 6273 Affinity Capture-MS Homo sapiens 49 PRKACG   Two-hybrid Homo sapiens View the network

Pathways in which CDK17 is involved

No pathways found