Gene description for TDRD7
Gene name tudor domain containing 7
Gene symbol TDRD7
Other names/aliases CATC4
PCTAIRE2BP
TRAP
Species Homo sapiens
 Database cross references - TDRD7
ExoCarta ExoCarta_23424
Vesiclepedia VP_23424
Entrez Gene 23424
HGNC 30831
MIM 611258
UniProt Q8NHU6  
 TDRD7 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for TDRD7
Molecular Function
    mRNA binding GO:0003729 IDA
    protein binding GO:0005515 IPI
Biological Process
    lens morphogenesis in camera-type eye GO:0002089 IBA
    lens morphogenesis in camera-type eye GO:0002089 IMP
    spermatogenesis GO:0007283 IBA
    spermatogenesis GO:0007283 ISS
    post-transcriptional regulation of gene expression GO:0010608 IMP
    P granule organization GO:0030719 IBA
    piRNA processing GO:0034587 IBA
    lens fiber cell differentiation GO:0070306 IBA
    lens fiber cell differentiation GO:0070306 IMP
Subcellular Localization
    cytoplasm GO:0005737 ISS
    chromatoid body GO:0033391 ISS
    ribonucleoprotein granule GO:0035770 IDA
    P granule GO:0043186 IBA
 Experiment description of studies that identified TDRD7 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TDRD7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDK17 5128
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
2 MAGEA8  
Two-hybrid Homo sapiens
3 FTL 2512
Affinity Capture-MS Homo sapiens
4 FOXF2  
Affinity Capture-MS Homo sapiens
5 ATXN2 6311
Two-hybrid Homo sapiens
6 S100A2 6273
Affinity Capture-MS Homo sapiens
7 MRE11A 4361
Affinity Capture-MS Homo sapiens
8 VHL  
Two-hybrid Homo sapiens
9 CAMSAP2  
Proximity Label-MS Homo sapiens
10 GABPB1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 NUP43 348995
Proximity Label-MS Homo sapiens
12 FAM64A 54478
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 CIRBP 1153
Affinity Capture-MS Homo sapiens
14 ZNF768 79724
Affinity Capture-MS Homo sapiens
15 CHCHD2  
Affinity Capture-MS Homo sapiens
16 FRAT1 10023
Two-hybrid Homo sapiens
17 HSPA1A 3303
Cross-Linking-MS (XL-MS) Homo sapiens
18 TACC1 6867
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
19 ENO1 2023
Cross-Linking-MS (XL-MS) Homo sapiens
20 TDRD7 23424
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
21 CDKN2A 1029
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
22 PIPSL 266971
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TDRD7 is involved
No pathways found





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