Gene description for MSTO1
Gene name misato 1, mitochondrial distribution and morphology regulator
Gene symbol MSTO1
Other names/aliases LST005
MST
Species Homo sapiens
 Database cross references - MSTO1
ExoCarta ExoCarta_55154
Vesiclepedia VP_55154
Entrez Gene 55154
HGNC 29678
UniProt Q9BUK6  
 MSTO1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for MSTO1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    mitochondrion organization GO:0007005 IBA
    mitochondrion organization GO:0007005 IMP
    positive regulation of mitochondrial fusion GO:0010636 IMP
    mitochondrion distribution GO:0048311 IMP
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrial outer membrane GO:0005741 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified MSTO1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MSTO1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Tor1aip1  
Affinity Capture-MS Mus musculus
2 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
3 CCT8 10694
Affinity Capture-MS Homo sapiens
4 CCT3 7203
Affinity Capture-MS Homo sapiens
5 PDCL3 79031
Affinity Capture-MS Homo sapiens
6 NUP210P1  
Affinity Capture-MS Homo sapiens
7 GPR17 2840
Affinity Capture-MS Homo sapiens
8 LIPH 200879
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 CCT2 10576
Affinity Capture-MS Homo sapiens
10 DNAJA2 10294
Affinity Capture-MS Homo sapiens
11 CCT6A 908
Affinity Capture-MS Homo sapiens
12 NPTN 27020
Affinity Capture-MS Homo sapiens
13 DNA2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 HDDC3  
Two-hybrid Homo sapiens
15 UBE3A 7337
Two-hybrid Homo sapiens
16 EFNB1 1947
Affinity Capture-MS Homo sapiens
17 CCT4 10575
Affinity Capture-MS Homo sapiens
18 LAMP2 3920
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 CCNJL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 NR1H3  
Two-hybrid Homo sapiens
21 LPCAT1 79888
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 ACACA 31
Negative Genetic Homo sapiens
23 COMTD1 118881
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 ARHGAP25  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 CASP9 842
Two-hybrid Homo sapiens
26 C3orf18  
Affinity Capture-MS Homo sapiens
27 RPA3 6119
Proximity Label-MS Homo sapiens
28 NIN 51199
Proximity Label-MS Homo sapiens
29 NTRK1 4914
Affinity Capture-MS Homo sapiens
30 OLFM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 PARP1 142
Proximity Label-MS Homo sapiens
32 CACNG2  
Affinity Capture-MS Homo sapiens
33 Ufl1  
Affinity Capture-MS Mus musculus
34 F9 2158
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 Nedd1  
Affinity Capture-MS Mus musculus
36 CCDC96  
Affinity Capture-MS Homo sapiens
37 Fign  
Affinity Capture-MS Mus musculus
38 SEMA4C 54910
Affinity Capture-MS Homo sapiens
39 DEF8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 P2RY10  
Affinity Capture-MS Homo sapiens
41 EP300 2033
Two-hybrid Homo sapiens
42 TGM1 7051
Affinity Capture-MS Homo sapiens
43 OGT 8473
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which MSTO1 is involved
No pathways found





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