Experiment description of studies that identified MNS1 in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for MNS1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SNX32   Two-hybrid Homo sapiens 2 MNS1 55329 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 3 DISC1 27185 Two-hybrid Homo sapiens 4 UBE2N 7334 Affinity Capture-MS Homo sapiens 5 HSF1   Affinity Capture-MS Homo sapiens 6 KIAA0753   Two-hybrid Homo sapiens 7 MSN 4478 Affinity Capture-MS Homo sapiens 8 CEP63   Two-hybrid Homo sapiens 9 TXLNB   Two-hybrid Homo sapiens 10 IQCB1   Two-hybrid Homo sapiens 11 FAM9B   Affinity Capture-MS Homo sapiens 12 KRT34   Two-hybrid Homo sapiens 13 TNNI2 7136 Two-hybrid Homo sapiens 14 THOC7 80145 Two-hybrid Homo sapiens 15 EP400   Two-hybrid Homo sapiens 16 CCDC93 54520 Co-fractionation Homo sapiens 17 STMN3   Two-hybrid Homo sapiens 18 TRIM54   Two-hybrid Homo sapiens 19 RPL10A 4736 Cross-Linking-MS (XL-MS) Homo sapiens 20 KDM1A 23028 Two-hybrid Homo sapiens 21 GIGYF1   Two-hybrid Homo sapiens 22 UPF1 5976 Affinity Capture-MS Homo sapiens 23 KRT75 9119 Two-hybrid Homo sapiens 24 FCHSD2   Two-hybrid Homo sapiens 25 CDR2   Two-hybrid Homo sapiens 26 USHBP1   Two-hybrid Homo sapiens 27 RAB28 9364 Affinity Capture-MS Homo sapiens 28 EWSR1 2130 Two-hybrid Homo sapiens 29 ACTG1 71 Affinity Capture-MS Homo sapiens 30 TNNI1 7135 Two-hybrid Homo sapiens 31 CCND3   Two-hybrid Homo sapiens View the network

Pathways in which MNS1 is involved

No pathways found