Gene description for IL36G
Gene name interleukin 36, gamma
Gene symbol IL36G
Other names/aliases IL-1F9
IL-1H1
IL-1RP2
IL1E
IL1F9
IL1H1
IL1RP2
Species Homo sapiens
 Database cross references - IL36G
ExoCarta ExoCarta_56300
Vesiclepedia VP_56300
Entrez Gene 56300
HGNC 15741
MIM 605542
UniProt Q9NZH8  
 IL36G identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for IL36G
Molecular Function
    cytokine activity GO:0005125 IBA
    interleukin-1 receptor binding GO:0005149 IEA
Biological Process
    cytokine production GO:0001816 IBA
    inflammatory response GO:0006954 IBA
    immune response GO:0006955 IBA
    cell-cell signaling GO:0007267 TAS
    cytokine-mediated signaling pathway GO:0019221 IBA
    innate immune response GO:0045087 IEA
    cellular response to lipopolysaccharide GO:0071222 IBA
Subcellular Localization
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 IBA
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 IDA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified IL36G in sEVs
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Antibody array
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for IL36G
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZSCAN20  
Affinity Capture-MS Homo sapiens
2 BPHL 670
Affinity Capture-MS Homo sapiens
3 ADH1C 126
Affinity Capture-MS Homo sapiens
4 PPP2R2B 5521
Affinity Capture-MS Homo sapiens
5 GFER  
Affinity Capture-MS Homo sapiens
6 C18orf21  
Affinity Capture-MS Homo sapiens
7 AGPAT1 10554
Affinity Capture-MS Homo sapiens
8 SCGB1D1  
Affinity Capture-MS Homo sapiens
9 NHLRC2 374354
Affinity Capture-MS Homo sapiens
10 MOGAT3  
Affinity Capture-MS Homo sapiens
11 ZNF154  
Affinity Capture-MS Homo sapiens
12 ATP6AP2 10159
Affinity Capture-MS Homo sapiens
13 CDK15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 SSBP2  
Affinity Capture-MS Homo sapiens
15 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
16 ZC3HC1  
Affinity Capture-MS Homo sapiens
17 MYL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CERS3  
Affinity Capture-MS Homo sapiens
19 KLHL11  
Affinity Capture-MS Homo sapiens
20 RNF115  
Affinity Capture-MS Homo sapiens
21 MBNL1 4154
Affinity Capture-MS Homo sapiens
22 KIR3DS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 GABPA 2551
Affinity Capture-MS Homo sapiens
24 SIK1  
Affinity Capture-MS Homo sapiens
25 SARAF  
Affinity Capture-MS Homo sapiens
26 MCM2 4171
Affinity Capture-MS Homo sapiens
27 PIGT 51604
Affinity Capture-MS Homo sapiens
28 PINK1  
Affinity Capture-MS Homo sapiens
29 GOT1 2805
Affinity Capture-MS Homo sapiens
30 SSUH2  
Affinity Capture-MS Homo sapiens
31 NUDT3 11165
Affinity Capture-MS Homo sapiens
32 OR2A4 79541
Affinity Capture-MS Homo sapiens
33 APTX  
Affinity Capture-MS Homo sapiens
34 UBE2G1 7326
Affinity Capture-MS Homo sapiens
35 SLC37A4 2542
Affinity Capture-MS Homo sapiens
36 CCR1  
Affinity Capture-MS Homo sapiens
37 STX17 55014
Affinity Capture-MS Homo sapiens
38 SOX2  
Affinity Capture-MS Homo sapiens
39 PHF11 51131
Affinity Capture-MS Homo sapiens
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