Gene description for SECTM1
Gene name secreted and transmembrane 1
Gene symbol SECTM1
Other names/aliases K12
Species Homo sapiens
 Database cross references - SECTM1
ExoCarta ExoCarta_6398
Vesiclepedia VP_6398
Entrez Gene 6398
HGNC 10707
MIM 602602
UniProt Q8WVN6  
 SECTM1 identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SECTM1
Molecular Function
    cytokine activity GO:0005125 IEA
    protein binding GO:0005515 IPI
    receptor ligand activity GO:0048018 IDA
Biological Process
    positive regulation of T cell cytokine production GO:0002726 IDA
    immune response GO:0006955 IEA
    signal transduction GO:0007165 IEA
    mesoderm development GO:0007498 TAS
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 HMP
Subcellular Localization
    extracellular space GO:0005615 TAS
    Golgi apparatus GO:0005794 TAS
    plasma membrane GO:0005886 IDA
    membrane GO:0016020 IBA
    membrane GO:0016020 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified SECTM1 in sEVs
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SECTM1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CCDC109B 55013
Affinity Capture-MS Homo sapiens
2 GAPDHS 26330
Affinity Capture-MS Homo sapiens
3 RYK 6259
Affinity Capture-MS Homo sapiens
4 ANKRD46 157567
Two-hybrid Homo sapiens
5 CLEC4A  
Affinity Capture-MS Homo sapiens
6 CD7  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
7 EMP3 2014
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SECTM1 is involved
No pathways found





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