Experiment description of studies that identified EMP3 in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for EMP3

Protein Interactor ExoCarta ID Identification method PubMed Species 1 NDUFS4 4724 Affinity Capture-MS Homo sapiens 2 IFNGR2   Two-hybrid Homo sapiens 3 CLDN2 9075 Two-hybrid Homo sapiens 4 MS4A3   Two-hybrid Homo sapiens 5 MR1   Two-hybrid Homo sapiens 6 SMIM3   Two-hybrid Homo sapiens 7 FNDC9   Two-hybrid Homo sapiens 8 SLC30A2   Two-hybrid Homo sapiens 9 ALG5 29880 Affinity Capture-MS Homo sapiens 10 OCLN 100506658 Affinity Capture-MS Homo sapiens 11 GJA5 2702 Two-hybrid Homo sapiens 12 SIGLECL1   Two-hybrid Homo sapiens 13 NDUFA9 4704 Affinity Capture-MS Homo sapiens 14 LDLRAD1   Two-hybrid Homo sapiens 15 SCPEP1 59342 Affinity Capture-MS Homo sapiens 16 TM4SF18   Two-hybrid Homo sapiens 17 KIR3DL3   Two-hybrid Homo sapiens 18 SECTM1 6398 Two-hybrid Homo sapiens 19 VSIG1   Two-hybrid Homo sapiens 20 LGALS3 3958 Affinity Capture-MS Homo sapiens 21 ATP6V0A2 23545 Affinity Capture-MS Homo sapiens 22 ERGIC3 51614 Two-hybrid Homo sapiens 23 CD47 961 Affinity Capture-MS Homo sapiens 24 POTEI 653269 Affinity Capture-MS Homo sapiens 25 NDUFA12 55967 Affinity Capture-MS Homo sapiens 26 LRRC4C   Two-hybrid Homo sapiens 27 CD79A   Two-hybrid Homo sapiens 28 LHFPL5   Two-hybrid Homo sapiens 29 CLDN7 1366 Two-hybrid Homo sapiens 30 IL3RA   Two-hybrid Homo sapiens 31 CREB3L1   Two-hybrid Homo sapiens 32 MTMR9 66036 Affinity Capture-MS Homo sapiens 33 SPACA1 81833 Two-hybrid Homo sapiens 34 LEUTX   Two-hybrid Homo sapiens 35 PLEKHB2 55041 Two-hybrid Homo sapiens 36 ND4 4538 Affinity Capture-MS Homo sapiens 37 EDA   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 38 CREM   Two-hybrid Homo sapiens 39 NDUFA2 4695 Affinity Capture-MS Homo sapiens 40 AAAS 8086 Affinity Capture-MS Homo sapiens 41 NDUFB3 4709 Affinity Capture-MS Homo sapiens 42 NDC1 55706 Affinity Capture-MS Homo sapiens 43 PHF6   Affinity Capture-MS Homo sapiens 44 ELOVL7 79993 Two-hybrid Homo sapiens 45 ATP6V0A1 535 Affinity Capture-MS Homo sapiens 46 MUC1 4582 Two-hybrid Homo sapiens 47 LYVE1   Two-hybrid Homo sapiens 48 GPR61   Two-hybrid Homo sapiens 49 TM9SF4 9777 Affinity Capture-MS Homo sapiens 50 GJB1 2705 Two-hybrid Homo sapiens 51 OPRM1 4988 Two-hybrid Homo sapiens 52 TMX2 51075 Two-hybrid Homo sapiens 53 KLRC1   Two-hybrid Homo sapiens 54 VANGL1 81839 Affinity Capture-MS Homo sapiens 55 SLAMF8   Two-hybrid Homo sapiens 56 GPA33 10223 Two-hybrid Homo sapiens 57 TSPAN12   Two-hybrid Homo sapiens 58 CD44 960 Affinity Capture-MS Homo sapiens 59 FAM210B   Two-hybrid Homo sapiens 60 RMDN3 55177 Two-hybrid Homo sapiens 61 SCAMP4 113178 Affinity Capture-MS Homo sapiens View the network

Pathways in which EMP3 is involved

No pathways found