Gene description for Cyb5b
Gene name cytochrome b5 type B
Gene symbol Cyb5b
Other names/aliases 1810044O22Rik
AU015618
Cyb5m
Species Mus musculus
 Database cross references - Cyb5b
ExoCarta ExoCarta_66427
Vesiclepedia VP_66427
Entrez Gene 66427
UniProt Q9CQX2  
 Cyb5b identified in sEVs derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Cyb5b
Molecular Function
    enzyme activator activity GO:0008047 IEA
    enzyme activator activity GO:0008047 ISO
    heme binding GO:0020037 IBA
    heme binding GO:0020037 IEA
    heme binding GO:0020037 ISO
    metal ion binding GO:0046872 IEA
    nitrite reductase (NO-forming) activity GO:0050421 IEA
    nitrite reductase (NO-forming) activity GO:0050421 ISO
Biological Process
    nitric oxide biosynthetic process GO:0006809 IEA
    nitric oxide biosynthetic process GO:0006809 ISO
Subcellular Localization
    mitochondrion GO:0005739 HDA
    mitochondrial outer membrane GO:0005741 IBA
    mitochondrial outer membrane GO:0005741 IEA
    mitochondrial outer membrane GO:0005741 ISO
    mitochondrial inner membrane GO:0005743 HDA
    intracellular membrane-bounded organelle GO:0043231 IBA
    nitric-oxide synthase complex GO:1903958 IEA
    nitric-oxide synthase complex GO:1903958 ISO
 Experiment description of studies that identified Cyb5b in sEVs
1
Experiment ID 188
MISEV standards
EM
Biophysical techniques
GAPDH|UCHL1|HSP90
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors "Lee HS, Jeong J, Lee KJ."
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Cyb5b
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Uchl5 56207
Co-fractionation Mus musculus
2 Tmem173  
Proximity Label-MS Mus musculus
View the network image/svg+xml



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