Gene description for Oxct1
Gene name 3-oxoacid CoA transferase 1
Gene symbol Oxct1
Other names/aliases 2610008O03Rik
Oxct
Oxct2a
Scot-s
Species Mus musculus
 Database cross references - Oxct1
ExoCarta ExoCarta_67041
Vesiclepedia VP_67041
Entrez Gene 67041
UniProt Q9D0K2  
 Oxct1 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Oxct1
Molecular Function
    succinyl-CoA:3-oxo-acid CoA-transferase activity GO:0008260 IBA
    succinyl-CoA:3-oxo-acid CoA-transferase activity GO:0008260 IDA
    succinyl-CoA:3-oxo-acid CoA-transferase activity GO:0008260 ISO
    identical protein binding GO:0042802 ISO
Biological Process
    positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 ISO
    ketone catabolic process GO:0042182 IMP
    ketone body catabolic process GO:0046952 IMP
    ketone body metabolic process GO:1902224 IBA
    ketone body metabolic process GO:1902224 IDA
    ketone body metabolic process GO:1902224 ISO
Subcellular Localization
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Oxct1 in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Oxct1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Csl  
Cross-Linking-MS (XL-MS) Mus musculus
2 Atxn1  
Affinity Capture-MS Mus musculus
3 Atp5a1 11946
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
4 Oxct1 67041
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
5 Mapt  
Affinity Capture-MS Mus musculus
6 Ssbp1  
Cross-Linking-MS (XL-MS) Mus musculus
7 Mdh2 17448
Cross-Linking-MS (XL-MS) Mus musculus
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