Gene description for F13a1
Gene name coagulation factor XIII, A1 subunit
Gene symbol F13a1
Other names/aliases 1200014I03Rik
AI462306
F13a
Species Mus musculus
 Database cross references - F13a1
ExoCarta ExoCarta_74145
Vesiclepedia VP_74145
Entrez Gene 74145
UniProt Q8BH61  
 F13a1 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for F13a1
Molecular Function
    protein-glutamine gamma-glutamyltransferase activity GO:0003810 IBA
    protein-glutamine gamma-glutamyltransferase activity GO:0003810 IMP
    protein-glutamine gamma-glutamyltransferase activity GO:0003810 ISO
    protein-glutamine gamma-glutamyltransferase activity GO:0003810 ISS
    metal ion binding GO:0046872 IEA
Biological Process
    blood coagulation GO:0007596 IMP
    peptide cross-linking GO:0018149 IMP
    peptide cross-linking GO:0018149 ISO
    peptide cross-linking GO:0018149 ISS
    blood coagulation, fibrin clot formation GO:0072378 IBA
    blood coagulation, fibrin clot formation GO:0072378 IMP
    blood coagulation, fibrin clot formation GO:0072378 ISO
    blood coagulation, fibrin clot formation GO:0072378 ISS
Subcellular Localization
    extracellular region GO:0005576 IEA
    cytoplasm GO:0005737 IEA
    collagen-containing extracellular matrix GO:0062023 HDA
 Experiment description of studies that identified F13a1 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for F13a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Fgg 99571
Co-fractionation Mus musculus
2 F13b  
Co-fractionation Mus musculus
View the network image/svg+xml



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