Gene description for ROGDI
Gene name rogdi homolog (Drosophila)
Gene symbol ROGDI
Other names/aliases KTZS
Species Homo sapiens
 Database cross references - ROGDI
ExoCarta ExoCarta_79641
Vesiclepedia VP_79641
Entrez Gene 79641
HGNC 29478
MIM 614574
UniProt Q9GZN7  
 ROGDI identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for ROGDI
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    brain development GO:0007420 IMP
    memory GO:0007613 IEA
    positive regulation of cell population proliferation GO:0008284 IEA
    response to xenobiotic stimulus GO:0009410 IEA
    gene expression GO:0010467 IEA
    neurogenesis GO:0022008 IMP
    hemopoiesis GO:0030097 IEA
    bone mineralization GO:0030282 IEA
    locomotion GO:0040011 IEA
    odontogenesis of dentin-containing tooth GO:0042475 IMP
    locomotor rhythm GO:0045475 IEA
    pH reduction GO:0045851 IEA
    neuromuscular process GO:0050905 IEA
    enamel mineralization GO:0070166 IEA
Subcellular Localization
    nuclear envelope GO:0005635 IDA
    synaptic vesicle GO:0008021 IEA
    axon GO:0030424 IEA
    dendrite GO:0030425 IEA
    perikaryon GO:0043204 IEA
    RAVE complex GO:0043291 IBA
    hippocampal mossy fiber to CA3 synapse GO:0098686 IEA
 Experiment description of studies that identified ROGDI in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ROGDI
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATP6V1H 51606
Affinity Capture-MS Homo sapiens
2 ATP1A2 477
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 DMXL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 ATP6V1B2 526
Affinity Capture-MS Homo sapiens
5 DISC1 27185
Two-hybrid Homo sapiens
6 MECP2 4204
Affinity Capture-MS Homo sapiens
7 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
8 MYH8 4626
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 KIF14 9928
Affinity Capture-MS Homo sapiens
10 TUBA3C 7278
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 ATG9A 79065
Proximity Label-MS Homo sapiens
12 ECT2 1894
Affinity Capture-MS Homo sapiens
13 ATP6V1G1 9550
Affinity Capture-MS Homo sapiens
14 KIF20A 10112
Affinity Capture-MS Homo sapiens
15 DMXL1 1657
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 KIAA1377  
Two-hybrid Homo sapiens
17 ATP6V1F 9296
Affinity Capture-MS Homo sapiens
18 AURKB 9212
Affinity Capture-MS Homo sapiens
19 XPO1 7514
Affinity Capture-MS Homo sapiens
20 CHMP4B 128866
Affinity Capture-MS Homo sapiens
21 ATP2A1 487
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 COPS6 10980
Two-hybrid Homo sapiens
23 CIT 11113
Affinity Capture-MS Homo sapiens
24 PRC1 9055
Affinity Capture-MS Homo sapiens
25 NUDT3 11165
Affinity Capture-MS Homo sapiens
26 MYH7 4625
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 WDR7 23335
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 ATP6V1E1 529
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ROGDI is involved
No pathways found





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