Gene description for DMXL1
Gene name Dmx-like 1
Gene symbol DMXL1
Other names/aliases -
Species Homo sapiens
 Database cross references - DMXL1
ExoCarta ExoCarta_1657
Vesiclepedia VP_1657
Entrez Gene 1657
HGNC 2937
MIM 605671
UniProt Q9Y485  
 DMXL1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for DMXL1
Biological Process
    vacuolar acidification GO:0007035 IBA
Subcellular Localization
    RAVE complex GO:0043291 IBA
 Experiment description of studies that identified DMXL1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for DMXL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DNAJC7 7266
Proximity Label-MS Homo sapiens
2 ATP6V1H 51606
Affinity Capture-MS Homo sapiens
3 ATP6V1B2 526
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 ROGDI 79641
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 RAB35 11021
Proximity Label-MS Homo sapiens
6 EBAG9 9166
Proximity Label-MS Homo sapiens
7 AGBL4  
Affinity Capture-MS Homo sapiens
8 RPN2 6185
Affinity Capture-MS Homo sapiens
9 LAMTOR1 55004
Proximity Label-MS Homo sapiens
10 RAB5A 5868
Proximity Label-MS Homo sapiens
11 LLGL1 3996
Affinity Capture-MS Homo sapiens
12 ATP6V1C2 245973
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 POGZ 23126
Two-hybrid Homo sapiens
14 SSSCA1 10534
Affinity Capture-MS Homo sapiens
15 ATG9A 79065
Proximity Label-MS Homo sapiens
16 LAMP2 3920
Proximity Label-MS Homo sapiens
17 CALM1 801
Reconstituted Complex Homo sapiens
18 ATP6V1G2  
Affinity Capture-MS Homo sapiens
19 ATP6V1F 9296
Affinity Capture-MS Homo sapiens
20 RAB4A 5867
Proximity Label-MS Homo sapiens
21 RNASEH2A 10535
Affinity Capture-MS Homo sapiens
22 PPP4R1L  
Affinity Capture-MS Homo sapiens
23 RAP1B 5908
Affinity Capture-MS Homo sapiens
24 ATP6V1G1 9550
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 SLC25A18  
Affinity Capture-MS Homo sapiens
26 RAB7A 7879
Proximity Label-MS Homo sapiens
27 RAB9A 9367
Proximity Label-MS Homo sapiens
28 GOLGA1  
Proximity Label-MS Homo sapiens
29 RAB3B 5865
Proximity Label-MS Homo sapiens
30 STT3B 201595
Affinity Capture-MS Homo sapiens
31 RPN1 6184
Affinity Capture-MS Homo sapiens
32 ATP6V1B1 525
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 STK4 6789
Affinity Capture-MS Homo sapiens
34 WDR7 23335
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 ATOH1  
Affinity Capture-MS Homo sapiens
36 DDOST 1650
Affinity Capture-MS Homo sapiens
37 ATP6V1E1 529
Affinity Capture-MS Homo sapiens
38 STX6 10228
Proximity Label-MS Homo sapiens
39 OST4  
Affinity Capture-MS Homo sapiens
40 RAB11A 8766
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which DMXL1 is involved
No pathways found





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