Gene description for CD2
Gene name	CD2 molecule
Gene symbol	CD2
Other names/aliases	LFA-2 SRBC T11
Species	Homo sapiens
Database cross references - CD2
ExoCarta	ExoCarta_914
Vesiclepedia	VP_914
Entrez Gene	914
HGNC	1639
MIM	186990
UniProt	P06729
CD2 identified in sEVs derived from the following tissue/cell type
T cells	11907077
Thymus	23844026

Gene ontology annotations for CD2

Molecular Function     signaling receptor binding GO:0005102 IBA     signaling receptor binding GO:0005102 IPI     protein binding GO:0005515 IPI     receptor tyrosine kinase binding GO:0030971 IEA     signaling receptor activity GO:0038023 NAS     identical protein binding GO:0042802 IEA Biological Process     membrane raft polarization GO:0001766 TAS     apoptotic process GO:0006915 TAS     immune response GO:0006955 IBA     cell surface receptor signaling pathway GO:0007166 TAS     natural killer cell activation GO:0030101 IBA     natural killer cell activation GO:0030101 IDA     natural killer cell activation GO:0030101 NAS     positive regulation of myeloid dendritic cell activation GO:0030887 NAS     positive regulation of type II interferon production GO:0032729 IDA     positive regulation of interleukin-8 production GO:0032757 IMP     positive regulation of tumor necrosis factor production GO:0032760 IDA     heterotypic cell-cell adhesion GO:0034113 IDA     T cell activation GO:0042110 TAS     natural killer cell mediated cytotoxicity GO:0042267 IDA     regulation of T cell differentiation GO:0045580 NAS     cell-cell adhesion GO:0098609 IBA     cell-cell adhesion GO:0098609 NAS Subcellular Localization     extracellular region GO:0005576 IEA     nucleoplasm GO:0005654 IDA     Golgi apparatus GO:0005794 IDA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 NAS     plasma membrane GO:0005886 TAS     cell-cell junction GO:0005911 IEA     external side of plasma membrane GO:0009897 IDA     cytoplasmic side of plasma membrane GO:0009898 IEA     cell surface GO:0009986 IDA     protein-containing complex GO:0032991 IEA