Gene description for CD5
Gene name CD5 molecule
Gene symbol CD5
Other names/aliases LEU1
T1
Species Homo sapiens
 Database cross references - CD5
ExoCarta ExoCarta_921
Vesiclepedia VP_921
Entrez Gene 921
HGNC 1685
MIM 153340
UniProt P06127  
 CD5 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CD5
Molecular Function
    protein binding GO:0005515 IPI
    signaling receptor activity GO:0038023 NAS
Biological Process
    cell recognition GO:0008037 NAS
    T cell costimulation GO:0031295 IBA
    apoptotic signaling pathway GO:0097190 IEA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 NAS
    external side of plasma membrane GO:0009897 IEA
 Experiment description of studies that identified CD5 in sEVs
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD2 914
Affinity Capture-Western Homo sapiens
2 RASA1 5921
Affinity Capture-Western Homo sapiens
3 CD6 923
FRET Homo sapiens
4 CBL 867
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
5 CD72  
Reconstituted Complex Homo sapiens
6 LCK 3932
Affinity Capture-Western Homo sapiens
7 EFNA1  
Affinity Capture-MS Homo sapiens
8 VAV1 7409
Co-fractionation Homo sapiens
9 Prkcg  
Biochemical Activity Rattus norvegicus
10 Prkca  
Biochemical Activity Rattus norvegicus
11 FYN 2534
Affinity Capture-Western Homo sapiens
12 CSNK2A1 1457
Biochemical Activity Homo sapiens
13 IDE 3416
Affinity Capture-MS Homo sapiens
14 Prkcb  
Biochemical Activity Rattus norvegicus
15 PPP1R7 5510
Affinity Capture-MS Homo sapiens
16 ZER1 10444
Affinity Capture-MS Homo sapiens
17 SPR 6697
Affinity Capture-MS Homo sapiens
18 PTPN6 5777
Affinity Capture-Western Homo sapiens
19 ZAP70 7535
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which CD5 is involved
No pathways found





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